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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 70 (1999), S. 2500-2506 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: Many sensors have been applied to the problem of measuring neutral atomic oxygen fluxes in low Earth orbit. The techniques used to date tend to suffer from several key disadvantages, variously: large mass and power budgets, large size, high cost, the ability to make only one measurement and poor time resolution. In this article preliminary results from ground-based testing of a novel atomic oxygen sensor based on a semiconducting metal oxide are reported. Such sensors are simple and relatively cheap while also requiring small power and mass budgets and, most importantly, are reusable. The sensors have been used in laboratory experiments to investigate the axial variation of atomic oxygen flux in a pulsed laser atomic oxygen source; the results compare well with readings taken with a carbon-coated quartz crystal microbalance. A small instrument based on these sensors has been designed and built for application on the UK's STRV-1c microsatellite. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0738
    Keywords: Differential spermatogenic response ; Dominant lethal mutations ; N-isopropyl-α-(2-methylhydrazino)-p-toluamide ; Procarbazine ; Mouse ; Spermatogenic cell killing
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A study was carried out on the effects of N-isopropyl-α-(2-methylhydrazino)-p-toluamide (procarbazine, Natulan®) in the dominant lethal test in the mouse. Male mice were dosed once and mated with fresh virgin females each week. The utilization of sperm, treated as spermatids or testicular sperm with 100–800 mg/kg, resulted in significant post-and pre-implantation death of embryos. Fertility was markedly reduced after the injection of 200 mg/kg of procarbazine and over. This is probably due to a cell killing effect, the most sensitive stages being differentiating spermatogonia, type A spermatogonia and resting primary spermatocytes. Total sterility was induced for several weeks with doses of 600 and 800 mg/kg. Up to 12 weeks after treatment the number of females with implants was still significantly lower than controls indicating a severe depletion of spermatogonial cells. The spectrum of effects correlates well with the drug's effect on nucleic acid and protein synthesis.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    The international journal of cardiovascular imaging 6 (1991), S. 145-156 
    ISSN: 1573-0743
    Keywords: intravascular ultrasound ; laser ; spark erosion ; atherectomy ; balloon angioplasty
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The increasing use of intravascular ultrasound technology by clinicians is providing detailed and immediate information about the results of interventions, and this is stimulating the development of new catheters that use ultrasound imaging to control therapy in real time. Cold and thermal balloon angioplasty, atherectomy, embolectomy, laser ablation and rotational recanalization are a few of the interesting capabilities now being added to ultrasound catheters. We report on the development and characteristics of some of these devices and attempt to assess their potential to precisely direct therapy.
    Type of Medium: Electronic Resource
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