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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 19 (2005), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Scleroderma is an autoimmune disease characterized by early inflammatory infiltrates followed by fibrosis in the skin and internal organs. CREST is a relatively benign cutaneous variant of scleroderma that features calcinosis, Raynaud's phenomenon, oesophageal dysfunction, sclerodactyly and telangiectases. Glomerulonephritis is a rare association of CREST. We are reporting a patient with CREST who developed glomerulonephritis and had anticentromere and antineutrophil cytoplasmic autoantibodies (ANCA) in her serum.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 185 (1960), S. 57-58 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] In the present investigation spheroplasts of Escherichia coli B were produced by the lysozyme versene treatment of Repaske4. With the aid of serological techniques it has been shown that (a) cell-wall antigens remain in carefully washed membrane preparations from the spheroplasts and (b) there are ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    BBA Section Nucleic Acids And Protein Synthesis 138 (1967), S. 133-139 
    ISSN: 0005-2787
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Chemistry and Physics of Lipids 6 (1971), S. 31-38 
    ISSN: 0009-3084
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Mineralogy and petrology 55 (1995), S. 145-157 
    ISSN: 1438-1168
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Zusammenfassung Im Gebiet von Fregeneda sind auf Grund ihrer Mineralogie, Morphologie, Internstruktur und Geländebeziehungen verschiedene Pegmatittypen zu unterscheiden. Am häufigsten sind einfache homogen aufgebaute Pegmatite. Zonar gebaute Li-Pegmatite sind ebenfalls weit verbreitet, Zinnstein-führende Pegmatite treten hingegen zurück, Die Pegmatite sind räumlich mit dem Lumbrales Granit, einem paraautochtonen, fein- bis mittelkörnigen Zwei-Glimmergranit, assoziiert, Dieser gehört einem der syntektonischen Massive, die während der dritten Phase der hercynischen Deformation deformiert wurden, an. Repräsentative, aus den verschiedenen Pegmatittypen separierte Glimmerminerale wurden untersucht, um zu klären, inwieweit die Pegmatite über einen direkten Fraktionierungspfad zu verbinden sind und in welcher Beziehung sie zu dem Lumbrales Granit stehen. Die Variation der Zusammensetzung der Glimmer hängt vom Pegmatittyp ab. Muscovite, die mit Li-Glimmern koexistieren, sind die relativ Al2O3-reichsten (32–37.7 Gew.%) und Fe- (0.2–1.5 Gew.%.) und Mg-ärmsten (0–0.3 Gew.%). Jene aus dem Lumbrales Granit sind die reich an MgO (0.5–0.7) und TiO2 (0.6–1.1 Gew.%). Die Gehalte von Sn (70–1168 ppm), Li (〈 5–22253 ppm). F (880-21470 ppm), Cs (〈 5–1696 ppm), Rb (800–9181 ppm) und anderer Spurenelemente nehmen mit der Entfernung vom Lumbrales Granit zu, während K/Rb abnimmt. Auf Grund dieses Verhältnisses sind die externen Li-führenden Pegmatite höher, die internen Pegmatite hingegen geringfügiger entwickelt. Erstere sind daher auch reicher an Cs, Li und Zn.
    Notes: Summary In the Fregeneda area different types of pegmatites can be recognized by their mineralogy, morphology, internal structure and field relationships. The most common type corresponds to a simple pegmatite with homogeneous internal structure, but zoned Li-bearing pegmatites also are relatively widespread. Cassiterite-bearing pegmatites are subordinate. The pegmatites are spatially associated to the Lumbrales granite. This is a parautochthonous, fine- to medium-grained, two-mica granite, one of the syntectonic massifs which were deformed during the third phase of Hercynian deformation. Representative micas selected from the different groups of pegmatites were studied to determine wether the pegmatites can be related by a common fractionation path, and how different pegmatite types are related to the spatially associated Lumbrales granite. Compositional variations in the micas depend on the pegmatite type. Muscovite coexisting with Li-micas in the Li-bearing pegmatites is one of the richest in Al2O3 (35.4–37.7 wt%) and the poorest in FeO (0.2–1.5 wt%) and MgO (0–0.3 wt%), whereas muscovite of the simple discordant pegmatites shows the highest FeO (2.2–3.3 wt%) and that from the Lumbrales granite is the richest in MgO (0.5–0.7 wt%) and TiO2 (0.6–1.1 wt%). On the other hand, Sn (70–1168 ppm), Li (〈 5–22253 ppm), F (880–21470 ppm), Cs (〈 5–1696 ppm), Rb (800–9181 ppm) and other trace elements seem to increase with distance from the Lumbrales granite, and K/Rb decreases. According to this ratio, the exterior Li-bearing pegmatites are the more evolved, whereas the interior pegmatites are less evolved, and are richer in Cs, Li and Zn than other pegmatite types.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0827
    Keywords: Key words: Dual X-ray absorptiometry — Cardiac transplantation — Bone markers — Vitamin D — Bone loss.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine , Physics
    Notes: Abstract. Cardiac transplantation is associated with severe bone loss caused by glucocorticoids, immunosuppressive treatment, and other factors. Treatment protocols for the prevention of bone loss is being studied. Forty patients who underwent cardiac transplantation were randomly given calcitonin (n= 13; 100 UI/d, nasal route), etidronate (n= 14; cyclical treatment 400 mg p.o./d/2 weeks/3 months), or calcidiol (n= 13; 32,000 IU/weekly) therapy for at least 18 months. Serum parameters (Ca, P, alkaline phosphatase, osteocalcin, intact PTH), urinary calcium, and vertebral mineral density (VMD; L2–L4, DXA Hologic QDR 1000) were measured immediately before treatment and after 6, 12, and 18 months of therapy after cardiac transplantation. Patients with cardiac transplantation had a VMD significantly lower than age and sex-matched Spanish controls. Prevalence of osteoporosis (Z-score below −2 SD) was 30%. Osteocalcin levels increased at 6, 12, and 18 months of treatment in the three groups. After 18 months of treatment, VMD increased significantly in the calcidiol 4.9%, vs. −1.19% and −0.19% in the calcitonin and etidronate groups, respectively. A lower incidence of fracture was found in patients treated with calcidiol during the study. In summary, we have found in this open randomized study that calcidiol was the most effective drug in the prevention and treatment of bone loss in patients after cardiac transplantation.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 63 (1968), S. 242-255 
    ISSN: 1432-072X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The fine structure of ungerminated and aerobically germinated sporangiospores of Mucor rouxii was compared. The germination process may be divided into two stages: I, spherical growth; II, emergence of a germ tube. In both stages, germination is growth in its strictest sense with overall increases in cell organelles; e.g., the increase in mitochondria is commensurate with the overall increase in protoplasmic mass. Noticeable changes occurring during germination are the disappearance of electron-dense lipoid bodies, formation of a large central vacuole and, most strikingly, formation of a new cell wall. Unlike many other fungi, M. rouxii does not germinate by converting the spore wall into a vegetative wall. Instead, as in other Mucorales, a vegetative wall is formed de novo under the spore wall during germination stage I. This new wall grows out, rupturing the spore wall, to become the germ tube wall. Associated with the apical wall of the germ tube is an apical corpuscle previously described. The vegetative wall exhibits a nonlayered, uniformly microfibrillar appearance in marked distinction to the spore wall which is triple-layered, with two thin electron dense outer layers, and a thick transparent inner stratum. The lack of continuity between the spore and vegetative walls is correlated with marked differences in wall chemistry previously reported. A separate new wall is also formed under the spore wall during anaerobic germination leading to yeast cell formation. On the other hand, in the development of one vegetative cell from another, such as in the formation of hyphae from yeast cells, the cell wall is structurally continuous. This continuity is correlated with a similarity in chemical composition of the cell wall reported earlier.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Clinical rheumatology 5 (1986), S. 33-38 
    ISSN: 1434-9949
    Keywords: Ro/SS-A Antigen ; Anti-Ro/SS-A Antibodies ; Antinuclear Antibodies
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The cellular localization of the Ro/SS-A antigen was defined using indirect immunofluorescence and eight monospecific anti-Ro/SS-A antisera which were identified by immunoblotting. Several mammalian tissues were used as substrates. The Ro/SS-A antigen was located mainly in the nucleus of dog liver and Hep-2-cells, and anti- Ro sera had produced a speckled staining pattern. Cytoplasmic fluorescence appeared only in one serum. IgG was the predominant immunoglobulin with anti-Ro/SS-A activity;five sera had complement fixing activity. The sera absorption studies with partially purified Ro/SS-A antigen and the negativation of the ANA tests had confirmed the specificity of our findings.
    Type of Medium: Electronic Resource
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