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  • 1
    ISSN: 1573-2568
    Keywords: COLITIS ; INFLAMMATION ; INFLAMMATORY BOWEL DISEASE ; COLON CANCER ; COLORECTAL CANCER ; NONHUMAN PRIMATE ; COTTON-TOP TAMARIN
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The cotton-top tamarin is a nonhuman primate noted for susceptibility to juvenile onset colitis and subsequent colon cancer. About 80% develop colitis in captive environments outside the tropics. The aim was to determine the prevalence of colitis and colorectal cancer in tamarins living wild in their tropical habitat. Endoscopic biopsy was used to compare severity of colitis, inflammatory/immune cell densities, mucosal dysplasia, and occurrence of cancer in wild tamarins in a tropical habitat with tamarins living captive in a temperate climate. Six colon biopsies from each of 69 captives showed severe colitis in 64.5% of biopsies and moderate colitis in 19.5% . Severe colitis was not found in 88 wild tamarins; 13% had moderate colitis. Densities of polymorphonuclear leukocytes, plasma cells, and mononuclear cells in the lamina propria were related directly to the severity of four grades of colitis (normal, mild, moderate, and severe). Histologic or gross signs of carcinoma were detected in 12 captives and low- or high-grade dysplasia in 15. Neither cancer nor dysplasia was found in any of the wild tamarins. The observations suggest that colitis and cancer in the tamarin model are linked to environmental factors.
    Type of Medium: Electronic Resource
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  • 2
    Publication Date: 2024-03-21
    Language: English
    Type: article , doc-type:article
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  • 3
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 109 (1998), S. 1930-1938 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The static structure of a bulk electrolyte solution or colloid system is investigated in the framework of a dressed-ion theory (DIT). The number–number, charge–number, and charge–charge static structure factors are calculated and are seen to depend only on the linear response function of the DIT α(circumflex)(k), the α function therefore determining the charge structure of the fluid in what is an expression of the fluctuation–dissipation theorem. The expression of the static structure factors for one-component charged spheres (OCCS) is evaluated in the random-phase approximation and in a modified version of the mean-spherical approximation (MSA), using the hard-sphere fluid as a reference system, and an explicit expression for the linear response function and dielectric function is obtained. The effective screening length (κ−1) and the transition from monotonic exponential to oscillatory behavior obtained from the modified MSA expression of the α function are seen to improve the ones derived from the second moment condition at intermediate concentrations. The internal charge density distribution of a dressed ion and the renormalized ion charges (q*) are also investigated. The oscillatory behavior of the charge distributions suggests an "onionlike model," with the central ion surrounded by spherical charge shells. The effective charges calculated from the modified MSA are seen to diverge in the neighborhood of the transition from the monotonic exponential regime to the oscillatory regime. In the limit of vanishing concentration, Debye–Hückel (DH) results are recovered.© 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 98 (1994), S. 8666-8672 
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The temperature dependence of the fundamental band-gap E0 of Cd1−xZnxTe alloys with zinc concentrations in the 0 to 0.3 range has been determined by modulated photoreflectance (PR). E0 is found to vary from 1.511 eV for x=0.00 to 1.667±0.008 eV for x=0.3, at room temperature and from 1.602 eV at x=0.00 to 1.762±0.004 eV for x=0.3 at 10 K. The measured broadening parameters Γ have values between 25 and 45 meV at room temperature and decrease monotonically to values around 5 meV or smaller at 10 K. The temperature dependence of the observed band gap energies is well described by the well known Varshni formula E(T)=E(0)−AT2/(T+aitch-theta) for all samples studied. The PR temperature broadening is well understood assuming that it results from the scattering of the excitonic electron-hole pair responsible of the band-to-band transition PR signal off LO phonons. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 113 (2000), S. 292-296 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The exact Ornstein–Zernike formalism for ionic fluids is seen to be equivalent to the dressed-ion theory (DIT), therefore proving the exact character of this mean-field formalism. The modified mean spherical approximation (MMSA) [Varela et al., J. Chem. Phys. 109, 1930 (1998)] is a modified version of the mean spherical approximation, which corrects some of the deficiencies of the original version of this closure relation in the prediction of the effective screening length. The MMSA effective non-Debye decay length, developed in the framework of the dressed-ion transport theory (DIT) of Kjellander and Mitchell, is an improvement on those of other theoretical and numerical schemes, which include self-consistent second moment approaches, asymptotic expansions, and nonlinear Debye–Hückel approximations. The MMSA screening length is used to analyze thermodynamic magnitudes of the charged fluid such as the internal energy and the osmotic coefficient and the results are seen to fit accurately to hypernetted chain calculations. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 111 (1999), S. 10986-10997 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The concentration dependence of the electrical conductance of several symmetrical electrolytes is studied using the dressed-ion transport theory (DITT) formalism. This theoretical scheme is constructed from the Fuoss–Onsager theory using the equilibrium dressed-ion theory (DIT) distribution functions for electrolyte and colloid media. The conductance equation is constructed from previous results for the relaxation of the ionic atmosphere [Varela et al., J. Chem. Phys. 110, 4483 (1999)], now completed with the calculation of the concentration-dependent electrophoretic velocity of ions on the basis of a DIT in a hydrodynamic point of view. Onsager's limiting law for the electrophoretic velocity based on the Debye–Hückel (DH) equilibrium distribution function is reformulated in terms of the DIT renormalized quantities, effective charges and effective screening length. The electrophoretic correction to the velocity calculated in the framework of this DITT is shown to exhibit a nontrivial dependence on the renormalized dielectric constant of the medium (ε*). The concentration dependence of both the deviations of the renormalized dielectric constant from the classical limit and the electrophoretic correction to the mobility is analyzed using the modified-mean spherical approximation (MMSA) value of the DIT linear response function α(circumflex)(k). The behavior of ε* and therefore of the electrophoretic correction to the ionic (or colloidal) mobilities is studied for both the random-phase approximation (RPA) and the MMSA and they are related to ionic association through the dimensionless coupling parameter, ζ, made up from the ratio between the Bjerrum length and the mean ionic radius. The expression for the conductance of the electrolyte solutions obtained in this new theoretical approach is cast in the form of a generalized Onsager's limiting law with a concentration-dependent slope which is predicted in terms of the formation of DIT renormalized quasiparticles in the solution. Conductance predictions of several theoretical expressions for the renormalized magnitudes of electrolyte solutions are compared to direct experimental data of KCl, and are in very good agreement with the theoretical predictions of the mean-field DITT, which confirms the convenience of understanding transport processes in terms of effective dynamical entities with renormalized ionic charges interacting by means of a renormalized screened potential. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 110 (1999), S. 4483-4492 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The dynamic response of a bulk electrolyte or colloid solution to an external field is investigated on the basis of a dressed-ion theory (DIT) in a hydrodynamic point of view. The radial part of the perturbed electric field acting on a given ion is explicitly calculated in terms of the DIT quantities derived from the linear response function calculated from the modified mean-spherical aproximation (MMSA) and its static and frequency-dependent limits are analyzed. In the static case, the asymptotic behavior is analyzed and Onsager's result is reformulated in terms of the effective charges and effective screening length and in the limit of vanishing concentration Debye–Falkenhagen–Onsager results are recovered. In the frequency-dependent DIT transport theory a relation between the field frequency and the time of relaxation of the ionic atmosphere is shown to be needed in order to get real renormalized charges and screening lengths. A decay of the perturbed electrostatic field as the inverse square root of the field frequency is obtained at high frequency and vanishing concentration along with a model-independent phase factor between the external and internal fields. The radial dependence of the perturbed average potential in the neighborhood of a quasiparticle is also calculated in the static case and several behaviors ranging from classical Derjaguin–Landau–Verwey–Overbeek colloidal stability theory interaction to pure attraction and repulsion are obtained. The results are analyzed in terms of a splitting of the ionic cloud into three different parts each one contributing to the radial dependence of the perturbed potential. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 87 (2000), S. 8113-8121 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A comparative study of electronic transport properties of p-Si wafers intentionally contaminated with Fe was performed using infrared photothermal radiometry (PTR) and microwave photoconductance decay (μ-PCD). Strong correlations were found between PTR and μ-PCD lifetimes in a lightly contaminated wafer with no significant PTR transient behavior. The absolute PTR lifetime values were larger than the local averaged μ-PCD values, due to the different excitation wavelengths and probe depths. In a heavily contaminated wafer the μ-PCD and PTR lifetime correlation was poorer. PTR measurements were highly sensitive to iron concentration, most likely due to the dependence of the bulk recombination lifetime on it. Rapid-scanned (nonsteady-state) PTR images of the wafer surface exhibited strong correlations with both μ-PCD lifetime and [Fe] concentration images in both heavily and lightly contaminated wafers. For the lightly and uniformly contaminated wafer, PTR scanning imaging was found to be more sensitive to iron concentration and lifetime variations than μ-PCD images. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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