ISSN:
1573-2568
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary A 29-year-old female patient had severe peptic ulcer disease associated with Zollinger-Ellison syndrome caused by a large islet cell carcinoma of the pancreas. She was treated successfully for 44 months with large doses of anticholinergic drugs. After the removal of the pancreatic tumor, a 50% gastrectomy, and a vagotomy, there was marked reduction of gastric secretion, and the patient remained symptom-free for 44 months. She had two successful pregnancies, one prior to and one after the tumor had been removed. At her request, further pregnancies were prevented by an intrauterine contraceptive device. When peptic ulcer symptoms and gastric hypersecretion recurred, the patient was again explored. The pancreas appeared normal and no metastatic lesions could be found. At this time she had a total gastrectomy with colonic interposition. Serum gastrin levels, assayed on two occasions, approximately 2 years later, were elevated. Almost 3 years later the patient feels well, is working daily, and maintains her weight at 135 lb.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02236028
Permalink