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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 781 (1996), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 656 (1992), S. 0 
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European archives of oto-rhino-laryngology and head & neck 224 (1979), S. 153-153 
    ISSN: 1434-4726
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Journal of computational neuroscience 8 (2000), S. 5-18 
    ISSN: 1573-6873
    Keywords: finite volume simulator ; vestibular maculae ; calyx ; backpropagation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Medicine , Physics
    Notes: Abstract A quasi-three-dimensional finite-volume numerical simulator was developed to study passive voltage spread in vestibular macular afferents. The method, borrowed from computational fluid dynamics, discretizes events transpiring in small volumes over time. The afferent simulated had three calyces with processes. The number of processes and synapses, and direction and timing of synapse activation, were varied. Simultaneous synapse activation resulted in shortest latency, while directional activation (proximal to distal and distal to proximal) yielded most regular discharges. Color-coded visualizations showed that the simulator discretized events and demonstrated that discharge produced a distal spread of voltage from the spike initiator into the ending. The simulations indicate that directional input, morphology, and timing of synapse activation can affect discharge properties, as must also distal spread of voltage from the spike initiator. The finite volume method has generality and can be applied to more complex neurons to explore discrete synaptic effects in four dimensions.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 197 (1980), S. 375-376 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Electron micrographs of otoconia of fetal mice, as obtained by Nakahara and Bevelander, provide morphological evidence that the otoconia consist of both organic material and calcium carbonate (calcite), contrary to their own conclusions. Calcite is an integral component of otoconia, apparently from their inception. The concept of mineralization by calcite of an already developed organic template (“preotolith”) is shown to be in error.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 139 (1974), S. 449-481 
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Histochemical, x-ray analytical and scanning and transmission electron microscopical procedures have been utilized to determine the chemical nature, physical appearance and attachments of the tectorial membrane in normal rats and to correlate these results with biochemical data on protein-carbohydrate complexes. Additionally, pertinent histochemical and ultrastructural findings in chemically sympathectomized rats are considered. The results indicate that the tectorial membrane is a viscous, complex, colloid of glycoprotein(s) possessing some oriented molecules and an ionic composition different from either endolymph or perilymph. It is attached to the reticular laminar surface of the organ of Corti and to the tips of the outer hair cells; it is attached to and enclose the hairs of the inner hair cells. A fluid compartment may exist within the limbs of the “W” formed by the hairs on each outer hair cell surface. Present biochemical concepts of viscous glycoproteins suggest that they are polyelectrolytes interacting physically to form complex networks. They possess characteristics making them important in fluid and ion transport. Furthermore, the macromolecular configuration assumed by such polyelectrolytes is unstable and subject to change from stress or shifts in pH or ions. Thus, the attachments of the tectorial membrane to the hair cells may play an important role in the transduction process at the molecular level.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The rat acoustic nerve is separated into central and peripheral portions by an astrocytic glial dome which is convex peripheralward. The long central portion is of typical central nervous system structure with narrow extracellular space (100-200 Å in width), oligodendrocytes and astrocytes. The glial dome is penetrated by acoustic nerve fibers at a node of Ranvier; the basal lamina of the astrocytes is reflected back over the peripheral Schwann cells at this site. Centrally, the myelin is thinner than peripherally.Acoustic nerve neurons, ranging in size from 25-60 μ, occur in the central portion of the nerve and may be divided into two groups based upon size and density of organelles: large and medium-sized. All the neurons possess an eccentric nucleus and a peripheral clear zone in the perikaryon beneath which Nissl substance is aggregated, but the medium-sized neurons have fewer organelles than the large cells. Dendrites and axons are similar in ultrastructure.While collagenous fibrils, fibroblasts, Schwann cells and extensive extracellular space occur in the peripheral portion of the nerve, no structure corresponding to perineurium or epineurium exists. Instead, dura mater surrounds the acoustic nerve within the modiolus and the pia mater encloses bundles of nerve fibers up to the modiolar foramina where it is reflected back as arachnoid mater. Nerve fibers traversing the modiolar foramina are devoid of a meningeal or perineurial covering; this condition also prevails in the osseous spiral lamina, although wisps of pia-like cells enclose groups of ganglion cells and nerve fibers in the spiral tract. These findings may help to explain acoustic nerve involvement in pathological processes such as meningitis and encephalitis.
    Type of Medium: Electronic Resource
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