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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 190 (1961), S. 349-350 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The present investigation involves the use of a comparatively simple and effective technique which has facilitated systematic study of this problem without the use of drugs, hormones, or pituitary transplantation. It is the result of an incidental observation made by one of us (A. B. K.) that trans ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of neural transmission 13 (1956), S. 179-191 
    ISSN: 1435-1463
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 1. Es wird die charakteristische Reaktion hypophysärer und hypothalamischer Neurosekretion auf Stress beschrieben. Sie tritt im Gefolge einer Reihe von Reizen auf, die Schmerz, Furcht oder Zorn umfassen, und ist der Intensität und Dauer des Reizes annähernd proportional. 2. Sie wird durch Ätheranästhesie, jedoch nicht durch die Anwendung von Chloroform, Nembutal oder Chloralose hervorgerufen. Bei anästhesierten Tieren sind keine weiteren Wirkungen von Schmerzreizen oder osmotischen Reizen feststellbar. Chloroform ist das Agens der Wahl, wenn man die Tiere zu opfern beabsichtigt, ohne die neurosekretorische Morphologie zu ändern. 3. Die Menge des Neurosekretes, bei dem nicht gereizten adrenalektomierten Tier wird herabgesetzt, jedoch bleibt die neurosekretorische Reaktion auf Stress im Gefolge von Adrenalektomie und adrenaler Demedullation erhalten. 4. Es wird angenommen, daß die färbbare neurosekretorische Substanz das morphologische Äquivalent des Hypophysenhinterlappenhormons ist, Unterscheidungen zwischen Hormon und Trägersubstanz werden als unnötig bezeichnet. Die Rolle der neurosekretorischen Substanz wird in Beziehung auf bekannte antidiuretische Hormonreaktionen, adrenale Insuffizienz und pituitäre Freisetzung von ACTH auf Stress besprochen.
    Notes: Summary 1. The characteristic response to stress of hypophysial and hypothalamic neurosecretory material is described. It is encountered following a variety of stimuli involving pain, fear, or rage and is roughly proportional to the intensity and duration of the stimulus. 2. It is produced by ether anaesthesia, but not by the administration of chloroform, Nembutal or chloralose. In anaesthetized animals no further effects of pain or osmotic stimuli are detectable. Chloroform is the agent of choice when it is desired to sacrifice animals without altering neurosecretory morphology. 3. The amount of neurosecretory material in the unstimulated adrenalectomized animal is reduced but the neurosecretory response to stress persists following adrenalectomy and adrenal demedullation. 4. It is believed that the stainable neurosecretory substance is the morphological equivalent of posterior pituitary hormone and distinctions between hormone and carrier-substance are considered unnecessary. The role of the neurosecretory substance is discussed in relation to known anti-diuretic hormone responses, adrenal insufficiency, and the pituitary release of ACTH following stress.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 115 (1953), S. 21-41 
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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