Digitale Medien
Oxford, UK
:
Blackwell Publishing Ltd
Clinical and experimental dermatology
16 (1991), S. 0
ISSN:
1365-2230
Quelle:
Blackwell Publishing Journal Backfiles 1879-2005
Thema:
Medizin
Notizen:
In this study, the bioavailability of fluconazole and ketoconazole in the stratum corneum and oral mucosa after multiple oral dosages were compared. It is well recognized that such evaluation is heavily dependent on the test methods employed. A method of culture of fungi on human stratum corneum and superficial mucosal cells, a model close to the in-vivo situation, was used. A significant difference in the bioavailability of the two antifungals in stratum corneum and superficial cells of oral mucosa was found. The activity of ketoconazole proved to be more rapid against T. mentagrophytes while fluconazole appeared slightly more active against C. albicans.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1111/j.1365-2230.1991.tb00338.x
Permalink
Bibliothek |
Standort |
Signatur |
Band/Heft/Jahr |
Verfügbarkeit |