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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Neuroscience and behavioral physiology 14 (1984), S. 326-333 
    ISSN: 1573-899X
    Keywords: habituation ; visceral systems ; neurons
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The general regularities of habituation in visceral systems according to the Thompson-Spencer criteria were investigated in acute experiments on chloralose-narcotized cats. Changes in systemic reactions (blood pressure and heart rate) and dynamics of neuronal activity in the medulla oblongata and cerebral cortex to repeated long stimulation of visceral (splanchnic and mesenteric) nerves were used as indicators of habituation. It was established that habituation in visceral systems develops more easily in the projection areas of the cortex than in the nuclei of the medulla oblongata. A comparison of the process of habituation in primary and secondary areas of the cortex and nuclei of the medulla oblongata revealed a number of differences in the time and expressivity of the investigated phenomenon: it occurred more rapidly in nonspecific structures of the brain. Recording of the EP in area SI to repeated stimulation of the pelvic nerves of nonnarcotized cats showed that complete habituation is not attained, and there is only a tendency toward a decrease of the amplitude of responses.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-9007
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Effects of dalargin, a synthetic leu-enkephalin analogue and its antagonist naloxone on synaptic transmission in afferent synapses of ray electroreceptors were investigated using an isolated preparation of Lorenzini ampullae from Black sea rays. It was shown that dalargin (10−6–10−10 mole liter) both decreased background activity and evoked activity of an afferent fiber in a dose-dependent manner. Naloxone (10−5 mole/liter) also inhibited afferent impulsation and completely blocked responses of the Lorenzini ampullae to dalargin application. L-glutamate-induced excitatory responses were reduced in the presence of dalargin. It is suggested that the modulatory action of dalargin on glutamatergic synaptic transmission in the Lorenzini ampullae is exerted via specific opiate receptors.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-9007
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The method of superfusion of the basal membranes of the ampullae of Lorenzini of skates was used to investigate the influence of L-serine-O-phosphate (SOP) on the background and evoked activity of afferent nerve fibers, as well as on the effects of application of agonists: exciting amino acids — L-glutamate (L-GLU), kainate (KA), quisqualte (Q), and N-methyl-D-aspartate (NMDA). It was found that SOP (threshold concentration 10−7 M) had an inhibiting effect on the background and evoked activity of the nerve fibers; depending on the concentration it decreased the stimulatory effects of L-GLU and NMDA and did not change the responses due to application of KA and Q. The data obtained suggest that the effects of SOP observed in the ampullae of Lorenzini are associated with its interaction with NMDA-type amino acid receptors.
    Type of Medium: Electronic Resource
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