Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Journal of cutaneous pathology
3 (1976), S. 0
ISSN:
1600-0560
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Skin biopsies from two patients with prurigo nodularis were studied with the electron microscope. Lesions were found in the cutaneous myelinated and unmyelinated nerves. Schwann-cell cytoplasm showed large irregular, membrane-bound, electron-lucent vacuoles. Unmyelinated axons were distended and devoid of neurotubules and neurofilaments. Myelinated nerves showed various degrees of demyelination. Onion-bulb formations with a centrally located myelinated fibre were also observed and numerous mast cells were found in the cellular infiltrate. All these findings indicate the presence of a chronic peripheral neuropathy, the etiology of which remains to be determined.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1600-0560.1976.tb01103.x
Permalink
Library |
Location |
Call Number |
Volume/Issue/Year |
Availability |