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  • 1
    ISSN: 0942-0940
    Keywords: Keywords: Stereotaxy; stereotactic procedures; magnetic resonance imaging; biopsy.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary ¶ Background. We present the results of 100 consecutive magnetic resonance (MR)-guided biopsies in cases where computerised tomography (CT) guiding was considered dangerous or impossible. Method. MR guiding was preferred to CT guiding for cases where lesions were located in the central area, or were not clearly visible on CT scan, or where the visualization of vessels was considered necessary. For most of the patients, calculation of target co-ordinates was performed using dedicated software enabling trajectory previsualization. There were 62 cases of contrast enhanced lesions, 32 cases of lesions without contrast enhancement, and 6 cases of very small lesions appearing hyperintense on T2-weighted images. Findings. Biopsies allowed a histological diagnosis in 92 cases. In 8 cases, the biopsy was negative (necrosis, gliosis or normal brain tissue). Three patients had a transient worsening of their neurological disturbances. Two patient had a non-regressive loss of motor function. No patient died. Interpretation. MR guiding for stereotactic biopsies was effective for CT-invisible or ill-defined lesions, lesions located in functional or densely vascularized areas and in the brain stem. The rate of postoperative complications was equivalent to or less than that reported in series of CT-guided biopsies.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 140 (1998), S. 429-436 
    ISSN: 0942-0940
    Keywords: Keywords: Chiari malformation; posterior cranial fossa; syringomyelia; Three-dimensional computerized tomography.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Malformations of the cranio-cervical junction represent a complex entity, comprising neuro-meningeal and bone anomalies. Malformations of the central nervous system are nowadays easily explored using magnetic resonance imaging (MRI), while osseous malformations are classically assessed with standard radiographic techniques, which can give only incomplete information, and are often difficult to realize and analyse. We report a retrospective study of 10 patients with a Chiari malformation operated on in our department at La Salpétrière hospital, between July 1995 and December 1996 (1 man, 9 women; mean of age: 35 years; postoperative median follow-up: 6 months,; 70% of improvement and 20% of stabilisation), and we underline the interest of the systematic pre-operative realization of a 3D CT and angio-CT studies of the cranio-cervical junction. This examination offers advantages of: ¶– a precise analysis of the more complex osseous malformations; ¶– a study of the relationships between vascular and bony structures; ¶– a study of the relationships between neuraxis and spinal and cranial structures; ¶– and an optimal planning of the surgical procedure, adapted to the anatomical particularities of the patient.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 36 (1994), S. 316-317 
    ISSN: 1432-1920
    Keywords: Intracranial aneurysm ; MRI ; Spontaneous thrombosis ; giant aneurysm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In a 23-year-old woman CT demonstrated a patent giant intracranial aneurysm. MRI, CT and angiography one month later demonstrated complete spontaneous thrombosis of the aneurysm. The diagnosis was confirmed surgically and pathologically. This case demonstrates that a normal angiogram can be associated with a thrombosed giant aneurysm, and that this diagnosis should be considered in cases of angiographically-occult cerebral vascular malformations.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 39 (1997), S. 394-399 
    ISSN: 1432-1920
    Keywords: Key words Pituitary adenoma ; Acromegaly ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Adenomas causing acromegaly represent at least a quarter of pituitary adenomas. We studied 12 patients presenting with active acromegaly due to a pituitary adenoma with a 1.5 T superconductive MRI unit. All had T1-weighted sagittal and coronal sections before and after Gd-DTPA; six had coronal T2-weighted images. Surgical correlation was obtained in seven patients. Histologically, there were eight growth hormone (GH)-secreting and three mixed [GH and prolactin (PRL) secreting] adenomas, and one secreting GH, PRL and follicle-stimulating hormone. Macroadenomas (10) were more frequent than microadenomas (2). No correlation was found between serum GH and tumour size. There were nine adenomas in the lateral part of the pituitary gland; seven showed lateral or infrasellar invasion. Homogeneous, isointense signal on T1- and T2-weighted images was observed in six cases. Heterogeneous adenomas had cystic or necrotic components.
    Type of Medium: Electronic Resource
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