ISSN:
1860-1499
Keywords:
Malignant fibrous histiocytoma
;
Larynx
;
Electron microscopy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Malignant fibrous histiocytoma (MFH) of the vocal cord occurring in a 46-year-old male was studied immunohistochemically and ultrastructurally. The tumor consisted of the two main areas, pleomorphic and storiform. Immunohistochemical staining was strongly positive for α1-antitrypsin and α1-antichymotrypsin, and negative for desmin, keratin, myoglobin, actin, carcinoembryonic antigen, and S100 protein. Ultrastructurally, this MFH consisted of four different types of cells which were either fibroblast-like, histiocyte-like, myofibroblast-like, or with features of both the fibroblast and histiocyte types. Transition forms between the four types of cells were also found. This suggests that cells of MFH are derived from the same undifferentiated stem cells.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02347973
Permalink
