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Remodelling chromatin with RNA (1997)

Willard, Huntington F. ; Salz, Helen K.

[s.l.] : Nature Publishing Group

Nature 386 (1997), S. 228-229

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] One of the fundamental differences between males and females is the number of X chromosomes. Because some functions of the X chromosome require equal expression in the two sexes, several types of dosage-compensation system have evolved that have the effect of attenuating the possible phenotypic ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/386228a0

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An interchromosomal gene conversion of the Drosophila dunce locus identified with restriction site polymorphisms: A potential involvement of transposable elements in gene conversion (1987)

Pittler, Steven J. ; Salz, Helen K. ; Davis, Ronald L.

Springer

Molecular genetics and genomics 208 (1987), S. 315-324

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ISSN: 1617-4623

Keywords: Gene conversion ; Transposable elements

Source: Springer Online Journal Archives 1860-2000

Topics: Biology

Notes: Summary Females heterozygous for the two alleles dnc 2 and dnc M14 of the X-linked gene dunce (dnc), and carrying a copy of dnc + progeny X-chromosomes from recombination experiments. Restriction site polymorphisms have been used as genetic markers to follow the parentage of dnc locus segments in these chromosomes. All six chromosomes are identical with respect to the spectrum of restriction site markers they carry in the dnc + chromosomal region. In the progeny chromosomes, this region is comprised of sequences like the dnc M14 X-chromosome and the translocation copy of dnc +. Sequences flanking the dnc gene in the progeny chromosomes are like the dnc M14 chromosome. Internal to the gene but near the 5′ end, is a segment from the dnc + translocation which has apparently originated from an interchromosomal and premeiotic gene conversion event. In addition, two transposable elements have inserted into the progeny chromosomes, one towards the 5′ end of dnc and the other near the 3′ end. The insertion of these elements occurred premeiotically since all six chromosomes are structurally identical. The data are interpreted with respect to a potential role of transposable element transposition in the process of gene conversion.