ISSN:
1573-8221
Keywords:
Anthio
;
turpentine
;
pneumonia
;
surfactant
;
ectases
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The nature and specificity of the damaging effect of an Anthio-tarred turpentine combination and the changes it produces are studied in acute, subacute, and chronic experiments on cats. Anthio, a compound capable accumulating in adipose tissues and destroying lipid-containing structures (for example, surfactant), induces characteristic destructive effects on lung alveoli and causes dystelectasis and the formation of ectases, which are observed in acute experiments. The ectases contain an oxyphilic serous exudate and microfocal lymphoid-cellular clusters in the alveolar wall and are characterized by microcirculatory disorders such as edema, capillary and venous stases, and microhemorrhages. Study of the combined effect of Anthio and turpentine shows that the Anthio-induced destruction is persistent and probably creates conditions for secondary damaging factors which aggravate the pathological process and broaden the spectrum of the morphological alterations characteristic of acute pneumonia.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02445718
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