ISSN:
1600-0765
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
The purpose of this study was to determine the effect of hydrogen peroxide delivered into periodontal pockets on gingival fluid flow and myeloperoxidase activity in the gingival fluid. Twenty systemically healthy human subjects presenting with moderate to advanced periodontitis were utilized. One side of the maxilla served as the control and the contralateral segment served as the experimental side. Measurements were made 0.5, 24, and 168 hours postoperatively. The experimental side was treated with 0.03 % hydrogen peroxide and the control side received distilled water. Five milliliters of fluid was delivered into the periodontal pockets either by sonication or passive dispersion. The 30 minute results indicated a mean increase in gingival fluid myeloperoxidase of 8.08 units per milliliter (U/ml) for the sonicated hydrogen peroxide, 2.05 U/ml for the passively dispersed hydrogen peroxide, 1.31 U/ml for the sonicated distilled water, and 0.60 U/ml for the passively dispersed distilled water. The values for hydrogen peroxide both sonicated and passively dispersed were significantly greater than baseline readings (p 〈 0.01), and the sonicated value was significantly larger than the passively dispersed value.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1600-0765.1980.tb00276.x
Permalink
