ISSN:
1612-1112
Keywords:
Size exclusion chromatography
;
Proteins
;
Optimization of resolution
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary Optimization strategies for improvement of peak capacity in size exclusion chromatography (SEC) of proteins with chemically modified silica columns are discussed. Decreasing flow rate and particle diameter and increasing the pore volume per unit column volume help to improve peak capacity in SEC.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02268796
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