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  • 1
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Electrical engineering 1 (1913), S. 538-539 
    ISSN: 1432-0487
    Source: Springer Online Journal Archives 1860-2000
    Topics: Electrical Engineering, Measurement and Control Technology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Human genetics 〈Berlin〉 65 (1984), S. 402-404 
    ISSN: 1432-1203
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary A new G6PD variant, designated Gd (+) Laguna, was found in a 9-year-old Brazillian boy of Portuguese ancestry suffering from an iron-refractory anemia. The red cell enzyme activity of the subject was 64%. The mutant enzyme showed slower electrophoretic mobility, increased affinity for glucose-6-phosphate, decreased affinity for NADP+, elevated utilization of substrate analogues, decreased inhibition of NADPH, normal heat stability and a biphasic pH curve. The occurrence of the variant in two non-anemic relatives of the propositus indicates that the association between this G6PD type and anemia may be coincidental.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 70 (1985), S. 72-79 
    ISSN: 1432-2242
    Keywords: Mice ; Selection experiments ; Plateau ; Fertility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A long-term experiment for increasing the traits first day litter size (LS1) and litter weight (LW1) was conducted with two populations for 33 generations. The selection plateau was reached in population DU-C (selection and estrus synchronization (h2 = 0.02±0.01); in population DU-K (selection) the plateau (h2 = 0.05±0.2) was nearly reached. Selection progress per generation was in LS1 b = 0.11±0.02; b = 0.12±0.04 (1st to 18th generation DU-K, DU-C) and b = 0.10±0.03; b = 0.07±0.05 (19th to 33rd generation, DU-K, DU-C) in LW1 b = 0.16±0.04 g; 0.19±0.07 g (DU-K, DU-C) b = 0.20±0.09 g; 0.001±0.09 g (DU-K, DU-C). Reverse and relaxe selection as well as systematic inbreeding was applied for 10 generations. Reverse selection yielded h2 = 0.28±0.11 (R-DU-K) and h2 = 0.17±0.05 (R-DU-C) and showed that there was still additive genetic variance. Relaxe selection did not cause alterations in the selection parameters, whereas inbreeding lead to inbred depressions (b = LS1 = −0.42±0.15; −0.45±0.12; b = LW1 = −1.13±0.20; −0.82±0.18 I-DU-K, I-DU-C). The plateau was based upon the heterozygote advantage. Several methods for overcoming the plateau were applied. A new selective useful variance could be created by crossing the plateau populations (h2 = 0.14±0.04). A short-term progress in overcoming the plateau (1st to 3rd generation) could be obtained by litter size standardization (LS = 388). Tandem selection (selection for body weight — BW42) as well as crossing of inbred strains were not suitable for overcoming the selection plateau. Altering the environmental conditions as a possibility for overcoming the plateau has been discussed.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Theoretical and applied genetics 75 (1987), S. 147-150 
    ISSN: 1432-2242
    Keywords: Mice ; Selection experiments ; Maternal effects litter size manipulation ; Fertility
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary A short-term selection experiment for increasing the first-day litter size (LS1) and 28-day litter weight (LW28) was conducted with three populations of mice over 8 generations. Different methods of litter size manipulation were used for the populations — in S the litter size was standardized to 8 (4 ♂ ♂, 4 ♀♀) on the first day, in LA it was adjusted to the average size of all litters born on the same day and NL had the natural litter size. To eliminate temporary environmental effects, a control population was kept in each case. The selection results per generation were, for LS 1 b=0.30 (S, NL) and 0.20 (LA), and for LW28 b=5.62 g (S), 5.26 g (NL), and 4.32 g (LA). The heritability obtained was between 0.18 and 0.13 for LS 1 and from 0.42 to 0.12 for LW28. The populations differed in the correlated responses for body weight parameters (litter weight gain). The implantation rate increased in populations S and NL (b=0.19, 0.37), but not in population LA. Postnatal mortality went down (b=-0.07) and the dam's milk production rose (b=1.11 g) only in population LA. The estimated partial regression coefficient linking body weight at mating (BWM) for the dam and the daughter's litter size showed an effect on the litter size.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Metrika 23 (1976), S. 77-82 
    ISSN: 1435-926X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary This paper describes nonparametric estimates of multivariate densities based on orthogonal series, a method evaluated byČencov [1962] for univariate density functions. Starting with the sample step function we show another way to get this estimator. Further we give a simple expression for mean integrated square error. Choosing the special case of trigonometric series this estimator is shown to be consistent.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International journal of anthropology 1 (1986), S. 229-238 
    ISSN: 1824-3096
    Keywords: Salivary Protein Variation ; demography ; caries ; Brazil ; Migration
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A total of 434 White and 148 Black persons from the southern Brazilian city of Porto Alegre were studied in relation to the Pr, Db, Pa, Ps and amylase electrophoretic salivary systems. Concomitantly, individual migration, parent-offspring and marital distances were recorded for these individuals, their spouses and ancestors. As far as these dispersion measures are concerned, White/Black and intergeneration differences were generally higher in the present study than in earlier ones, although the averages found this time were consistently lower than those observed before. The correlations between these measures indicated a higher degree of independence between generations than was previously inferred. In the genetic studies, 21 comparisons between the Porto Alegre distributions and those found in North American, European and African surveys yelded 7 significant differences. In general the allele frequencies in Porto Alegre show intermediate values between those found elsewhere among Blacks and Whites, suggesting admixture in these two racial segments of that city. Using previous estimates of such admixture the gene frequencies of the putative Porto Alegre parental populations were estimated and compared with present European and African results. Relatively large differences were observed for the Db+ andAmy 1 E markers only. No significant associations were detected between the salivary phenotypes and the prevalences of caried, extracted and filled teeth.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Metrika 23 (1976), S. 149-154 
    ISSN: 1435-926X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Summary Fór the estimation of the functional Δ (f)=∫f 2(x)dx Bhattacharyya andRoussas [1969] proposed an estimator based on the kernel-technique for density estimation. This paper describes a method, which rests on density estimations by orthogonal expansions. In the main we show the considered estimator to be consistent in the quadratic mean.
    Type of Medium: Electronic Resource
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