ISSN:
0075-4617
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Antimalarial 6-Aminoquinolines, II. 6-[ω-Diethylaminoalkylamino]- and 6-[ω-Aminoalkyl-amino]-5,8-dimethoxyquinaldinesTwelve derivatives of 6-amino-5,8-dimethoxyquinaldine with the basic side chains (C2H5)2N—(CH2)n—NH (n = 2, 3; 15, 16) and H2N—(CH2)n—CHR—NH— (n = 1 - 9, R = H, CH3; 21a-k) in the 6-position are prepared with the aim of studying the influence of the basic side chain on malarial activity and toxicity of the 6-aminoquinolines.
Notes:
Zwölf in 6-Stellung basisch alkylierte 6-Amino-5.8-dimethoxy-chinaldine mit den Seiten-ketten (C2H5)2N—(CH2)n—NH— (n = 2, 3; 15, 16) und H2N—(CH2)n—CHR—NH—(n = 1—9, R = H, CH3; 21a-k) wurden synthetisiert, um den Einfluß der basischen Seitenkette auf Malaria-Wirksamkeit und Toxizität der 6-Amino-chinoline zu untersuchen.
Additional Material:
3 Tab.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jlac.19717440115
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