ISSN:
1617-4623
Keywords:
Position-effect veriegation
;
Suppressor mutations
;
Germ-line mosaics
;
Maternal expression
;
Drosophila melanogaster
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary We have studied the developmental effects of two dominant suppressor mutations of position-effect variegation mutations on female germ-line cells. Su-var (2) 101, which has been shown to affect chromatin structure though altering histone deacetylation, and Su-var (3) 303are recessive female steriles and zygotic lethals in the presence of butyrate or an additional Y chromosome. We have analysed mosaic females with mutant germ-line and normal soma and concluded that intact functions of the Su-var (2) 1 and the Su-var (3) 3 genes are required for development of both the soma and the germ-line and that as indirect evidence suggest, their maternally provided products are needed for normal embryonic development. It is suggested that there is possibly a common control of chromatin structure and gene expression in the soma, female germ-line and embryonic cells of Drosophila.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00338393
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