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  • 1
    Electronic Resource
    Electronic Resource
    Learned maintenance of pain: Muscle tension reduces central nervous system processing of painful stimulation in chronic and subchronic pain patients (1999)
    Oxford, UK : Blackwell Publishing
    Psychophysiology 36 (1999), S. 0 
    Details
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: The effect of level of muscle tension on the perception of painful stimuli was assessed in 13 chronic back pain patients, 14 subjects at high risk for chronic back pain, and 14 matched healthy controls. Subjects received painful intracutaneous electric stimuli to the forearm or the lower back while they produced either high or low muscle tension levels. Visual analog scale (VAS) ratings of acute pain were obtained after each trial. Electroencephalograms, electromyograms, skin conductance levels, and blood pressure were measured during the trials. Although subjective pain ratings were not significantly affected by muscle tension levels, the chronic pain patients displayed elevated N150 and N150/P260 amplitudes of the somatosensory-evoked potentials in the low as compared to the high muscle tension condition. The high risk group showed a trend toward higher N150 amplitudes in the low as compared to the high tension condition. The results of this study partially support the hypothesis that increases in muscle tension might serve as a pain-reducing mechanism in chronic pain patients and those at risk for chronicity, thus leading to a vicious pain-tension cycle.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/1469-8986.3660755
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Symptom-Specific Psychophysiological Responses in Chronic Pain Patients. (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Psychophysiology 29 (1992), S. 0 
    Details
    ISSN: 1469-8986
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Psychology
    Notes: Symptom-specific psychophysiologiocal responding was assessed in 20 chronic back pain patients, 20 patients suffering from temporomandibular pain and dysfunction, and 20 matched healthy controls. Surface EMG from the lower and upper back, the masseter, and the biceps muscles, and heart rate and skin conductance level were continuously recorded during adaptation, resting baseline, and stressful and neutral imagery phases. Univariate and multivariate analyses of variance were performed on raw data as well as data corrected for autocorrelation. The results showed significantly higher EMG reactivity which was lateralized to the left side at the patients site of pain but not distal sites. This hyperreactivity was observed only during stressful imagery. The healthy controls displayed a significantly higher response in heart rate, but skin conductance level was not significantly different. The results are interpreted as indicative of idiosyncratic muscular response patterns to personally relevant situations at the site of pain in patients suffering from chronic muscular pain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1469-8986.1992.tb01718.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Cholinergic-rich brain transplants reverse alcohol-induced memory deficits (1988)
    [s.l.] : Nature Publishing Group
    Nature 332 (1988), S. 448-450 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Male Sprague-Dawley rats were subjected to a high level of alcohol intake for 28 weeks and, after a further four weeks free of alcohol, were tested in an eight-arm radial maze21 for memory function. Four of the eight arms were baited with reward and correct choices were defined either spatially (by ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/332448a0
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  • 4
    Electronic Resource
    Electronic Resource
    Discrimination of muscle tension in chronic pain patients and healthy controls (1992)
    Springer
    Applied psychophysiology and biofeedback 17 (1992), S. 165-177 
    Details
    ISSN: 1573-3270
    Keywords: EMG ; perception ; chronic back pain ; TMPD
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The purpose of this study was to assess the perception of muscle tension in chronic pain patients and healthy controls. Twenty chronic back pain patients, 20 patients who suffered from temporomandibular pain and dysfunction, and 20 healthy controls were instructed to produce eight different levels of muscle contraction in either the m. masseter or the m. erector spinae. Each level was produced three times; trials were presented in random order. Analyses of the accuracy and the sensitivity of discrimination of muscle tension levels revealed that the patients were less able to perceive muscle contraction levels correctly and that they underestimated their actual levels of muscle tension. Patients and controls did not differ in the extent to which they contracted muscles not involved in the task. Patients suffering from musculoskeletal disorders seem to display a genuine deficit in discrimination of muscle tension that is related to neither local physiological changes at the site of pain, lack of motivation, inattention, nor fatigue.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01000401
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    Paper (German National Licenses)
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