ISSN:
1546-170X
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Medicine
Notes:
[Auszug] Naturally pyrazinamide (PZA)–resistant Mycobacterium bovis and acquired PZA–resistant M. tuberculosis strains lose pyrazinamidase (PZase). To investigate the molecular mechanism of PZA resistance, we have cloned the gene (pncA) encoding M. tuberculosis PZase. Mutations in pncA were ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/nm0696-662
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