ISSN:
1440-1797
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Summary: Data on zinc status in Indian patients with chronic renal failure is lacking. There are conflicting data in the literature on plasma and erythrocyte zinc levels in renal failure patients and the effect of haemodialysis on zinc status. of the multiple factors believed to be involved in the pathogenesis of uraemic impotence, attention has been focused on the possible role of zinc depletion and hyperprolactinaemia. We report a longitudinal study on 27 patients with end-stage renal disease (ESRD). Plasma and erythrocyte zinc, serum prolactin and serum total testosterone were studied at diagnosis, 4 weeks after haemodialysis, and 3 and 6 months after successful renal transplantation. Zinc status and hyperprolactinaemia are both normalized within 6 months after renal transplantation. While there was a significant positive correlation between plasma zinc and serum testosterone, there was no correlation between serum prolactin and testosterone. This observation suggests that plasma zinc may be a more important determinant of normal gonadal function than prolactin in renal transplant recipients.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1440-1797.1997.tb00229.x
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