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  • 1
    Electronic Resource
    Electronic Resource
    Application of synchrotron radiation in investigation of metal-ion release from a hip replacement prosthesis (1998)
    Chester : International Union of Crystallography (IUCr)
    Journal of synchrotron radiation 5 (1998), S. 1136-1138 
    Details
    ISSN: 1600-5775
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: The aim of the present study was to measure very low concentrations of Al, V, Fe, Cr and other metal elements in a matrix of P, S, Cl, Ca and other constituent elements of the human body. These metal elements were released from a failed total hip replacement prosthesis into the surrounding tissues. The experimental results have been compared with those from proton-induced X-ray emission spectroscopy of the same specimen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0909049597020244
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  • 2
    Electronic Resource
    Electronic Resource
    Secondary ion mass spectrometry in the study of biomineralizations and biomaterials
    Amsterdam : Elsevier
    Journal of Chromatography B: Biomedical Sciences and Applications 562 (1991), S. 754 
    Details
    ISSN: 0378-4347
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0378-4347(91)80639-T
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  • 3
    Electronic Resource
    Electronic Resource
    Secondary ion mass spectrometry in the study of biomineralizations and biomaterials
    Amsterdam : Elsevier
    Analytica Chimica Acta 241 (1990), S. 299-314 
    Details
    ISSN: 0003-2670
    Keywords: Biomaterials ; Biomineralization ; Bone ; Teeth
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/S0003-2670(00)83660-0
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  • 4
    Electronic Resource
    Electronic Resource
    Bone augmentation at titanium implants using autologous bone grafts and a bioresorbable barrier. An experimental study in the rabbit tibia. (1997)
    Copenhagen : Munksgaard International Publishers
    Clinical oral implants research 8 (1997), S. 0 
    Details
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim of the present investigation was to compare the effect of using autologous bone particles covered with a bioresorbable matrix barrier with the use of bone particles alone on bone augmentation at titanium implants installed in the rabbit tibia. Two Brånemark System® implants, one in each tibia, were inserted in each of 9 rabbits in such a way that 5 threads were not covered with bone. Autologous bone particles were harvested from the skull and placed over the exposed implant surfaces on each tibia. The bone graft on one tibia was covered with a Guidor® Matrix Barrier, while the bone graft on the other tibia served as a control. After a healing period of 12 weeks, the animals were sacrificed and specimens taken for histomorphometrical analyses. The analyses showed that a significantly larger volume of augmented bone tissue had formed at the test sites. There were, however, no differences in the amount of mineralized bone. In fact, the difference in tissue volume was due to an increased amount of bone marrow at the test sites. The degree of mineralized bone to implant contact as well as the degree of mineralized bone within the threads at the test implants were similar to that at the controls. In conclusion, it was found that the coverage of particulate autologous bone grafts with a bioresorbable barrier resulted in a larger volume of augmented bone than the use of bone grafts not covered with a barrier.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0501.1997.080202.x
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  • 5
    Electronic Resource
    Electronic Resource
    Identification of bone quality in conjunction with insertion of titanium implants. A pilot study in jaw autopsy specimens. (1995)
    Copenhagen : Munksgaard International Publishers
    Clinical oral implants research 6 (1995), S. 0 
    Details
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Ten autopsy jaw specimens (6 mandibles. 4 maxillae) were used for cutting resistance measurements during low-speed threading. Overall, 31 sites were analyzed where implants were inserted into threaded canals. Bone area measurements were performed around the implants as described previously. The cutting resistance values together with the total bone area values were found to be higher in mandibles than in maxillae, and a tendency towards higher values was seen in incisor regions compared with premolar regions. Furthermore, an intraindividual comparison between the true cutting resistance and the bone density values of prepared sites showed a statistically significant correlation. The method with cutting resistance measurements for evaluation of bone quality seems therefore to be reliable, at least when used in human autopsy jaw bone specimens.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0501.1995.060403.x
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  • 6
    Electronic Resource
    Electronic Resource
    Evaluation of bone density using cutting resistance measurements and microradiography. An in vitro study in pig ribs. (1995)
    Copenhagen : Munksgaard International Publishers
    Clinical oral implants research 6 (1995), S. 0 
    Details
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A method using cutting resistance measurements during low-speed threading for identification of various bone densities has been evaluated with regard to its precision and potential. Pig ribs were used as test samples. Differing hand pressure, minor deviation (5") from a vertical tapping direction and individual threading did not reveal any significant differences in cutting resistance values. After implants were inserted into the threaded canals, the total bone as well as trabecular and compact bone areas surrounding the implants were calculated via a computer program and using microradiographs of the bone test samples. The outcome of the cutting resistance measurements was compared with that of the microradiographic technique, and good agreement was observed between the two procedures in the ability to identify bone density. Therefore, cutting resistance measurements may in the future also be used to clinically identify bone qualities in jaws
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0501.1995.060305.x
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  • 7
    Electronic Resource
    Electronic Resource
    Augmentation of intramembraneous bone beyond the skeletal envelope using an occlusive titanium barrier. An experimental study in the rabbit. (1995)
    Copenhagen : Munksgaard International Publishers
    Clinical oral implants research 6 (1995), S. 0 
    Details
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim of this investigation was to evaluate whether augmentation of intramembraneous bone beyond the skeletal envelope can be predictably achieved by placing a completely occlusive barrier on the skull bone of rabbits, hereby creating a secluded space with bone tissue being the only adjoining tissue. The experiment was carried out in 3 New Zealand white rabbits. In each animal, a midline incision was made down to the bone surface of the skull and a skin-periosteal flap was raised to expose the skull bone on both sides of the midline. Two prefabricated titanium domes with an inner diameter of 4.5 mm and an inner height of 3.0 mm were installed on each side. The domes were supplied with a horizontal, peripheral flange and a vertical edge, fitting tightly into a circular slit, prepared by a trephine into the skull bone. This arrangement ensured a stable anchorage of the dome and a reliable peripheral sealing of the space. The skin-periosteal flaps were relocated to cover the domes and sutured. After a healing period of 3 months, the animals were killed and the experimental areas excised and prepared for histological transversal ground sections with each dome in situ. The results demonstrated complete bone fill of all domes, with no signs of ingrowth of other types of tissues, indicating that the use of a barrier with total occlusiveness, sufficient stiffness and stability and reliable peripheral sealing will result in predictable bone augmentation of spaces also beyond the skeletal envelope.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0501.1995.060201.x
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  • 8
    Electronic Resource
    Electronic Resource
    Tissue reactions towards titanium implants inserted in growing jaws. A histological study in the pig. (1993)
    Copenhagen : Munksgaard International Publishers
    Clinical oral implants research 4 (1993), S. 0 
    Details
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In this investigation, the tissue reactions towards titanium implants inserted in growing jaws of pigs were studied by means of histology. At the age of 12 weeks, 5 test pigs each received 4 Brånemark System* titanium implants (fixtures). The fixtures were inserted immediately after extraction of the mesial root of the second deciduous premolar (P2) and the deciduous canine (C) on one side of the mandible and the mesial root of the first deciduous premolar (PI) on the other side. The fourth implant was placed after extraction of the deciduous lateral incisor (L) on one side in the upper jaw. Furthermore, 1 pig in which no extractions or fixture installations were performed served as a control. All pigs were followed for 165 days with clinical, radiographic and biometric examinations, the results of which have been previously presented. In this study, 10-μm-thick ground sections were produced for histology after the jaws had been fixed by immersion in formalin and further processed and embedded in plastic resin. Six of the fixtures originally inserted were lost during the experimental period, and the remaining implants were found to be involved with mineralized bone to varying degrees. Regarding the fixture-to-teeth relationship, it was found that, in the premolar region of the lower jaw, the teeth were positioned superior to and buccally angulated in relation to the fixtures. In the upper jaw, the implants were positioned below the adjacent teeth but centrally in the alveolar process. Tooth germs adjacent to the fixture had a displaced eruption path, buccally or lingually to the fixture. If the bud developed in close contact with the fixture, a changed morphology of the germ could be observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0501.1993.040202.x
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  • 9
    Electronic Resource
    Electronic Resource
    Augmentation of skull bone using a bioresorbable barrier supported by autologous bone grafts. An intra-individual study in the rabbit. (1997)
    Copenhagen : Munksgaard International Publishers
    Clinical oral implants research 8 (1997), S. 0 
    Details
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim of this experimental investigation was to compare the effect of using autologous particulate bone grafts with and without a bioresorbable barrier covering for augmentation of the rabbit skull bone. For this purpose, bilateral, circular, 8 mm wide and 1 mm deep skull bone defects were prepared and overfilled with particulate bone grafts. The grafts placed in the test sites were covered with a bioresorbable barrier (Guidor® Matrix Barrier). The grafts placed in the control sites were covered only by the repositioned, cutaneous flap. 12 weeks later, the animals were sacrificed, the experimental sites were defleshed and the height and volume of the augmented bone in the test and control sites were measured clinically. Histologically, morphometrical measurements of the bone tissue were performed in decalcified vertical cross-sections of the experimental sites. Statistically significant differences were found in favour of the coverage of the bone graft particles with the barrier, both with respect to the height and the volume of the augmented bone.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0501.1997.080203.x
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  • 10
    Electronic Resource
    Electronic Resource
    The effect of mechanical intervention on jaw bone density. An experimental study in the rabbit. (1995)
    Copenhagen : Munksgaard International Publishers
    Clinical oral implants research 6 (1995), S. 0 
    Details
    ISSN: 1600-0501
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The aim of this investigation was to test the hypothesis that jaw bone, subjected to mechanical intervention, will heal with increased density compared with conditions before the traumatic insult. The natural edentulous area between the incisor and the first molar on both sides of the maxillary jaw of 8 adult New Zealand white rabbits constituted the experimental model. On the test side, holes were drilled through the cortical plate and into the cancellous bone. No drilling was performed on the contralateral control side. One transversal ground section from each specimen, taken in the centre of and representing both the test and control site, was prepared to ensure that the same sagittal level of the jaw was represented. Morphometric measurements were performed and comprised assessments of the total cross-sectional area of 1) the edentulous part of the jaw, 2) the cortical bone plates and 3) the bone trabeculae and marrow spaces of the cancellous bone. The mechanical intervention resulted in a substantial alteration of the bone tissue morphology, the most conspicuous change being a markedly increased number of bone trabeculae per cancellous bone unit. Thus, the area occupied by bone trabeculae was about twice as large in the test sites compared with the control sites (+103%), whereas the area occupied by bone marrow cavities and cortical bone was significantly smaller. The clinical implications of the findings for potential treatment of fragile bone tissues and bone sites intended for implant insertion are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-0501.1995.060107.x
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