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  • 1
    Electronic Resource
    Electronic Resource
    1-Deprenyl test in migraine: neuroendocrinological aspects (1993)
    USA/Oxford, UK : Blackwell Science Ltd
    Cephalalgia 13 (1993), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We evaluated the effect of 1-deprenyl, a drug that increases the availability of endogenous dopamine, on the plasma levels of prolactin and growth hormone in 10 female patients with migraine and in 10 control subjects matched for age and menstrual phase. The patients showed a significant decrease in prolactin levels at 30, 60 and 120 min after the oral administration of 5 mg of 1-deprenyl when compared with the values obtained in controls (p 〈 0.001). The effects of 1-deprenyl on growth hormone plasma levels were not significantly different between patients and controls. These data suggest that 1-deprenyl inhibits prolactin release in migraine patients, but not in control subjects. This differential sensitivity could be explained by dopamine receptor supersensitivity in migraine patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1993.1306406.x
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  • 2
    Electronic Resource
    Electronic Resource
    Sex-hormone-related events in migrainous females. A clinical comparative study between migraine with aura and migraine without aura (1995)
    USA/Oxford, UK : American Association for the Study of Headache/Blackwell Science Ltd
    Cephalalgia 15 (1995), S. 0 
    Details
    ISSN: 1468-2982
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In this study, the relationship between hormonal-related events and migraine with aura (MA) and without aura (MO) was investigated. Subjects included 268 women suffering from MA (88) and MO (180). Data were collected on the relationship between sex-hormone-related events and migraine. Migraine during menses was observed in a significantly higher percentage of MO than MA patients (p 〈 0.03). Menstrual migraine was significantly more common in MO than in MA patients (p 〈 0.01). Migraine began during pregnancy in a significantly higher percentage of MA than of MO patients (p 〈 0.01). No significant difference was observed between the two groups of patients regarding the onset of migraine at menarche, after menopause, in the postpartum period or during the early cycles of oral contraceptives. Also, both groups of patients showed a similar migraine course during pregnancy, oral contraceptive use and menopause. Eight patients with coexisting migraine with aura and migraine without aura attacks reported the appearance of the aura symptom for the first time in the early cycles of oral contraceptive intake. These findings suggest that gonadal hormone fluctuation may influence both types of migraine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1468-2982.1995.015002140.x
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  • 3
    Electronic Resource
    Electronic Resource
    The scrapie agent and the prion hypothesis
    Amsterdam : Elsevier
    Trends in Biochemical Sciences 13 (1988), S. 309-313 
    Details
    ISSN: 0968-0004
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0968-0004(88)90126-0
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Supracerebellar arachnoid cyst and reversible tonsillar herniation: magnetic resonance imaging and pathophysiological considerations (1992)
    Springer
    Neuroradiology 34 (1992), S. 404-406 
    Details
    ISSN: 1432-1920
    Keywords: Supracerebellar arachnoid cyst ; Tonsillar herniation ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A large supracerebellar arachnoid cyst was associated with herniation of the cerebellar tonsils and deformity of the cervicomedullary junction in an adult. Magnetic resonance imaging showed partial restoration of normal anatomy following surgery and clinical improvement, which helped in the formulation of a etiopathogenetic hypotheses.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00596501
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Non-invasive assessment of neck-vessel pathology (1998)
    Springer
    European radiology 8 (1998), S. 691-697 
    Details
    ISSN: 1432-1084
    Keywords: Key words: Carotid bifurcation ; DSA ; Duplex ; Ultrasound ; MR angiography ; CT angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Clinical trials (NASCET, ECTS) have shown that carotid endarterectomy is protective against stroke in patients with symptomatic severe carotid stenosis. To decrease costs and risks, new diagnostic tools have been developed, such as duplex ultrasound (DUS), magnetic resonance angiography (MRA), and more recently computed tomography angiography (CTA). CTA and MRA provide excellent 3D angiography images of the extracranial vessels, using a volume-rendering technique. Digitally subtracted MRA (DSA-MRA) obtained with high-speed acquisitions during gadolinium injection has also recently become available. These techniques are changing the role of non-invasive assessment of carotid stenosis. Although it is probably too early to assess a definite diagnostic algorithm, the use of DSA as a pre-surgical tool for defining carotid stenosis is rapidly decreasing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003300050461
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Emotion-related cerebral asymmetry: hemodynamics measured by functional ultrasound (1999)
    Springer
    Journal of neurology 246 (1999), S. 1172-1176 
    Details
    ISSN: 1432-1459
    Keywords: Key words Transcranial Doppler ultrasound ; Emotions ; Evoked ; cerebral blood flow ; hemispheric dominance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study assessed the use of transcranial Doppler ultrasound in detecting selective changes in cerebral blood flow velocity during emotional processes. The role of the respective hemispheres in emotional processing is controversial. Cerebral control of emotional processing has previously been investigated by analysis of patients with unilateral brain damage, experiments with selective stimulation of only one hemisphere, and more recently by imaging techniques measuring local cerebral blood flow. We investigated mean flow velocity continuously and simultaneously in both the right and left middle cerebral arteries (MCAs) in 16 healthy right-handed young subjects at rest and during the performance of three tasks: task 1: 15 slides with nonemotional content; task 2: 15 slides with negative emotional content; task 3: 15 slides with nonemotional content with different content from that in task 1. The three tasks produced significantly different effects on the right and left hemispheres. During the two nonemotional tasks the increase in mean flow velocity over basal values was similar in the two MCAs (task 1: left MCA = 3.27 ± 1.9%; right MCA = 3.63 ± 2.1%; task 3: left MCA = 2.42 ± 0.7%; right MCA = 2.56 ± 1.3%); the negative emotional task was accompanied by a significantly higher increase in the right (11.31 ± 1.6%) than in the left MCA (4.72 ± 3.7%; analysis of variance two-way interaction: side of recording x task, F = 43.6, P 〈 0.001). These results show the possibility of obtaining specific functional information from bilateral transcranial Doppler ultrasound and suggest the involvement of the right hemisphere in emotional processing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004150050538
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Spontaneous subarachnoid hemorrhage in an HIV patient (1990)
    Springer
    Neurological sciences 11 (1990), S. 493-495 
    Details
    ISSN: 1590-3478
    Keywords: HIV ; seizures ; MR ; CSF examination ; thrombocytopenia ; subarachnoid hemorrhage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario In un paziente sieropositivo per HIV che presentò crisi tonico-cloniche generalizzate, la risonanza magnetica e l'esame del liquor dimostrarono i segni di una pregressa emorragia subaracnoidea. L'angiografia cerebrale non dimostrò malformazioni vascolari. Gli esami di laboratorio misero in evidenza una trombocitopenia autoimmune. Una emorragia subaracnoidea spontanea, indotta da una trombocitopenia, dovrebbe essere presa in considerazione in pazienti sieropositivi per HIV che presentino una sintomatologia neurologica anche aspecifica.
    Notes: Abstract In an HIV-seropositive patient presenting generalized tonic-clonic seizures, magnetic resonance imaging and cerebrospinal fluid examination disclosed the signs of a previous subarachnoid bleed. No vascular malformation was observed with cerebral angiography. Laboratory tests revealed an autoimmune thrombocytopenia. A spontaneous subarachnoid hemorrhage induced by thrombocytopenia should be considered when investigating HIV patients presenting even non-specific neurological symptoms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02336570
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    Paper (German National Licenses)
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