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  • 1
    Electronic Resource
    Electronic Resource
    Investigations on the neural tissue-limb deplant of the salamander (1968)
    Springer
    Experimental brain research 6 (1968), S. 81-88 
    Details
    ISSN: 1432-1106
    Keywords: Nerve ; Limb ; Transplant ; Salamander ; Neuropharmacology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Pharmacological, electrophysiological, and histological studies have been performed on a nerve-limb deplant in the dorsal limb of the axolotl salamander. The preparation, which consists of a limb and a segment of spinal cord transplanted contiguously in a host salamander, exhibits spontaneous electrical and contractile activity a few weeks after transplantation. By electromyographic recording it has been possible to study the response of the preparation to a variety of transmitter substances and neuropharmacological agents and to determine their locus of action on the preparation. Cholinoceptive regions appear to be present at the myoneural junction as well as in the innervating neurons. Glutamic acid has an excitatory and γ-aminobutyric acid an inhibitory effect on the neuronal cell bodies. The preparation offers a unique opportunity to investigate developmental, neurochemical, and functional correlations in the nervous system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00239163
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Evolution of the extracellular space in immature nervous tissue (1968)
    Springer
    Cellular and molecular life sciences 24 (1968), S. 929-930 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Resumen En el cerebelo de rata recién nacida existen espacios extracelulares mayores que 1000 Å los cuales progresivamente se reducen hasta que en la tercera semana, como en el adulto, las celulas y fibras se hallan separadas por endiduras de 150–200 Å. Estas observaciones indican que el reducido espacio usualmente hallado en el adulto no es un artificio tecnico como ha sido sugerido por algunos autores.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02138661
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Focal brain hyperthemia. I. The cerebellar cortex (1978)
    Springer
    Cellular and molecular life sciences 34 (1978), S. 479-481 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Focal brain hyperthemic methodology has been described and data presented on the cerebellum which show that enhancement of electrical activity of cerebellar cortex occurs when this method is used with careful monitoring of temperature. The duration of electrically induced cerebral after-discharges is shortened when cerebellar warming reaches 39.5–42.0°C. Since these effects are repeatable over many hours, there appears to be little, if any, resultant damage. Such induced changes in the cerebrum resemble those previously reported in which electrical stimuli were applied to the cerebellar cortex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01935939
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    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Cilia in axolotl neurons (Siredon mexicanum) (1970)
    Springer
    Cellular and molecular life sciences 26 (1970), S. 774-776 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Resumen Un estudio electro-microscópico de la médula espinal del axalote reveló la existencia de neuronas ciliadas, tanto en medulas normales como en segmentos medulares implantados por tiempos variables en la aleta dorsal de animales de la misma especie. La cilia que es única e implantada cerca de una dendrita se extiende en la neuropila por una longitud de varios μm.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02232544
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Alterations in forebrain catecholamine metabolism produced by cerebellar lesions in the rat (1977)
    Springer
    Journal of neural transmission 40 (1977), S. 115-128 
    Details
    ISSN: 1435-1463
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Projections from the midline cerebellar nuclei to norepinephrine (NE) and dopamine (DA) cell groups in the brain stem have been demonstrated histologically. To determine if these connections are significant biochemically, unilateral electrolytic lesions were placed in either vermis or paravermis and levels of DA, NE and gamma-aminobutyric acid (GABA) were measured in each half of the forebrain at 1 1/2, 3 or 6 weeks. In the cerebral hemisphere ipsilateral to a vermis lesion, there was a decrease in NE levels at 3 and 6 weeks. Relative to the opposite side DA was also reduced at 3 and 6 weeks. Paravermal lesions caused a contralateral reduction in DA at 3 weeks but no change in NE. GABA was only slightly altered. These results suggest that the cerebellum can modify levels and turnover of catecholamines in the brain, possibly via direct anatomic connections as well as by functional interaction with catecholaminergic pathways.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01250563
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    Paper (German National Licenses)
    Fulltext
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