ISSN:
0009-2940
Keywords:
Chemistry
;
Inorganic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Contributions to the Chemistry of Indole, VI. Syntheses of Compound Similar to Eserine, I A New Synthesis of the Eserine SkeletonStarting from the methylphenylhydrazone of ethyl 3-formylbutyrate (6) the lactone 7 is synthesized. 7 reacts quantitatively with methylamine to yield the lactam 4, which is reduced by LiAlH4 to give 1 („desoxoeseroline“) in almost quantitative yield.
Notes:
Aus dem Methylphenylhydrazon des 3-Formylbuttersäureesters 6 wird das Lacton 7 erhalten, welches mit Methylamin quantitativ zum Lactam 4 reagiert. Dieses wird mit Lithiumalanat quantitativ zu 1 („Desoxoeserolin“) reduziert.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/cber.19751080126
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