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  • 1
    Electronic Resource
    Electronic Resource
    A Series of N4-Imidoethyl Derivatives of 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine as 5-HT1A Receptor Ligands: Synthesis and Structure-Affinity Relationships (1995)
    s.l. : American Chemical Society
    Journal of medicinal chemistry 38 (1995), S. 4303-4308 
    Details
    ISSN: 1520-4804
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/jm00021a020
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  • 2
    Electronic Resource
    Electronic Resource
    Infrared spectra of hydrogen-bonded ion–radical complexes: I−⋅HCH2 and Br−⋅HCHBr (1999)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 111 (1999), S. 10464-10468 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We report the preparation and infrared spectra of the CH3I− and CH2Br2− anions formed by argon cluster-mediated electron attachment to the neutral molecular precursors. Infrared predissociation spectra were acquired for both the bare and argon-solvated species in the C–H stretching region. Partial rotational structure was recovered in the CH3I− system, consistent with the hydrogen-bonded, C2v structure suggested in an earlier analysis of its photoelectron spectrum [J. Kim et al., J. Am. Soc. Mass Spectrom. 10, 810 (1999)]. The spectrum and photofragmentation pattern confirm that this species is trapped in a very weakly bound ion–methyl radical form (I−⋅HCH2) involving a single ionic H bond. The CH2Br2− anion displays a similar spectrum, where one CH stretch is significantly redshifted, again signaling the single H-bonding motif. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.480392
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  • 3
    Electronic Resource
    Electronic Resource
    Infrared spectroscopic observation of the argon isomer distribution in evaporative ensembles of I−⋅ROH⋅Arm (R=methyl, ethyl, isopropyl) clusters (1999)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 111 (1999), S. 9593-9599 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Vibrational predissociation spectra of argon-solvated iodide–alcohol clusters (I−⋅ROH⋅Arm, ROH=MeOH, EtOH, i-PrOH) are reported in the OH stretching region (3200–3400 cm−1). The spectra display multiple peaks associated with the ionic H-bonded OH stretching fundamental, which vary according to the extent of argon solvation. At small m, the number of peaks reflects the total number of attached argon atoms, such that peaks associated with fewer argons persist (with a small blue shift) in the spectra of the larger clusters, while new peaks appear red shifted by about 12 cm−1 with each additional argon. The effect saturates in a manner that depends on the particular alcohol (mmax=6 for MeOH, 5 for EtOH, and 4 for i-PrOH). We interpret these observations to indicate the presence of multiple isomers in the evaporative ensemble, which are distinguishable according to the different arrangements of argon atoms among two effective binding sites. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.480292
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  • 4
    Electronic Resource
    Electronic Resource
    Expression of human .alpha.2-macroglobulin cDNA in baby hamster kidney fibroblasts: secretion of high levels of active .alpha.2-macroglobulin (1990)
    s.l. : American Chemical Society
    Biochemistry 29 (1990), S. 4081-4087 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00469a009
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  • 5
    Electronic Resource
    Electronic Resource
    Dental state and functional capacity in 75-year-olds in three Nordic localities (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 22 (1995), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: summary The aims of the study were to compare dental state in three Nordic 75-year-old populations and to evaluate dental state as a marker of functional ageing. The study is part of a Nordic comparative study of 75-year-olds in Glostrup, Göteborg and Jyväskylä. In the dental studies, 411 subjects in Denmark, 308 in Sweden and 310 in Finland participated. Odontological history was obtained from interviews. Other methods, which are described elsewhere, were used to measure various functional parameters. In Goteborg, 23% of the 75-year-olds reported they were edentulous and 27% that they had more than 20 of their own teeth. The corresponding figures in Glostrup were 45% and 15% and in Jyväskylä 58% and 9%, respectively. In all three localities, economic factors and lifestyle factors, such as tobacco smoking, low physical activity and low social activity, were significant predictors for impaired dental health. The number of teeth was significantly associated with, for example, spirometry parameters, reaction time, body extention and body flexion in males. In females, significant associations were obtained with spirometry parameters, reaction time, handgrip, body extension and body flexion. Internordic differences regarding dental state were obvious. Dental state was associated with functional capacities. We suggest that dental state is a marker of functional capacity in elderly populations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.1995.tb01063.x
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  • 6
    Electronic Resource
    Electronic Resource
    Relationship between dental state and dietary intake in 70-year-old males and females in Göteborg, Sweden: a population study (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of oral rehabilitation 9 (1982), S. 0 
    Details
    ISSN: 1365-2842
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A representative sample of 368 70-year-old males and females in Göteborg, Sweden, participated in an odontological examination and a dietary interview. The aim of the study was to relate dental state to dietary habits and, furthermore, to study the possible influence of some social factors on these relations. The degree of dental invalidity was measured with Eichner's index. There was a highly significant correlation between this index and the number of teeth and tooth contacts. Dietary interviews were performed by a dietitian according to the dietary history method. Intake of several food items was significantly inversely related to the degree of dental invalidity in males but less so in females. The proportion of probands with insufficient intake of nutrients was in one or more respects higher among the edentulous than in the dentate and highest in the female edentulous probands with only one or no denture.Insufficient intakes of some nutrients were significantly related to the degree of dental invalidity. These relations remained unchanged in males but not in females when some socio-economic factors were introduced as confounding factors in a multivariate relation analysis; which might be due to the fact that these social factors play a more important role in females than in males.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2842.1982.tb01041.x
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  • 7
    Electronic Resource
    Electronic Resource
    Maximal isometric muscle strength and anthropometry in 75-year-old men and women in three Nordic localities (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Scandinavian journal of medicine & science in sports 4 (1994), S. 0 
    Details
    ISSN: 1600-0838
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine , Sports Science
    Notes: Isometric maximal strength of hand grip, elbow flexion, knee extension, trunk extension and trunk flexion was studied in representative samples of 75-year-old residents of 3 Nordic localities: Glostrup in Denmark, Gothenburg in Sweden and Jyväskylä in Finland. The study forms a part of a wider comparative research project analyzing the functional capacity and health of 75-year-olds in these towns. The strength measurements were carried out using standardized techniques and identical dynamometers. The results showed that the strength values of the limb muscles were significantly lower among the 75-year-olds in Jyväskylä, both in absolute values and in relative units (N/kg body mass). For the trunk muscles, the women in Glostrup had significantly lower strength values than their counterparts from the two other localities, while among men there were no significant differences. The isometric strength values correlated strongly with the anthropometric characteristics, especially lean body mass. This was true for all the muscle groups studied. The results thus indicated considerable differences in muscular strength between the 75-year-olds in the 3 Nordic localities. These differences may partly be due to differences in basic anthropometric characteristics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0838.1994.tb00402.x
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  • 8
    Electronic Resource
    Electronic Resource
    Masticatory ability in 80-year-old subjects and its relation to intake of energy, nutrients and food items (2002)
    Oxford, UK : Blackwell Publishing Ltd
    Gerodontology 19 (2002), S. 0 
    Details
    ISSN: 1741-2358
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective: The aim of the present study was to analyse the relationship between masticatory ability (self-assessed masticatory ability and bite force) and intake of energy, nutrients and food items in a population sample of elderly subjects.Design and Subjects: From a population sample of 80-year-old people, 160 individuals (74 men and 86 women) took part in an odontological study.Main Outcome Measures: A dental examination including bite force recording, a questionnaire focusing on self-assessed masticatory ability, and a dietary interview.Setting: Department of Geriatric Medicine, Göteborg University, Sweden.Results: The dental status among the participants varied much (from edentulous in both jaws - 22% - to more than 20 natural teeth - 30%). The mean maximum bite force was higher in men (165 N) than in women (105 N). Bite force was significantly correlated to the Eichner index and to the number of teeth. One third of the subjects reported no masticatory problem, whereas 18% identified 3 such problems. The intake of energy and nutrients varied much but the means were well above recommended values. The correlations between dental status and bite force on one side and dietary intake on the other side were in general weak and most often statistically non-significant. Impaired general health and reduced dentition were both associated with more masticatory problems.Conclusion: The examined sample of 80-year-old subjects had a great variation in dental status, bite force and self-assessed masticatory ability, but these factors had only a minor influence on dietary selection and intake, which on average were well above recommended values.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1741-2358.2002.00095.x
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  • 9
    Electronic Resource
    Electronic Resource
    Oral glucose clearance in nonagenarians in relation to functional capacity, medication and oral variables (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Gerodontology 14 (1997), S. 0 
    Details
    ISSN: 1741-2358
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives:To study oral sugar (glucose) clearance and to examine some factors which were believed to either influence or be dependent upon oral glucose clearance. Design:Cross-sectional, clinical study with analysis of records. Setting:Göteborg gerontological and geriatric population studies, Göteborg University, Sweden. Subjects:71 community-dwelling individuals, 27 men and 44 women, of a representative sample of 260 92-year-old persons. Intervention and Main outcome measures: Glucose concentration was measured in saliva after chewing of a glucose tablet and the clearance was assessed by three different variables: (i) the initial salivary glucose concentration, (ii) the area under the curve (AUC) and (iii) the clearance time. Results:The glucose clearance showed a wide inter-individual variation, which could be explained partly by differences in oral state, chewing time, stimulated salivary secretion rate and medication use. A positive correlation was found between the clearance variables and the number of lactobacilli and mutans streptococci in saliva and the percentage of untreated root caries lesions of the total number of exposed root surfaces. Conclusions: A slow oral sugar clearance is more common among 92-year-olds than younger adults earlier reported in other studies, particularly in those who have uncompensated functional impairments and a high medication history. A decreased oral glucose clearance was associated with high counts of salivary lactobacilli and mutans streptococci and a high proportion of untreated root caries lesions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1741-2358.1997.00017.x
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  • 10
    Electronic Resource
    Electronic Resource
    Associations between self-assessed masticatory ability and some general health factors in a Swedish population (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Gerodontology 13 (1996), S. 0 
    Details
    ISSN: 1741-2358
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives: The aims of this study were 1) to describe changes in self-assessed masticatory ability over a 14 year period (1975–89); and 2) to describe associations between self-assessed masticatory ability and age, dental state and some other background factors in a sample of the Swedish population in 1988/89. Design:The Swedish National Central Bureau of Statistics investigates annually the living conditions of the Swedish population by means of interviews by trained persons. The data were analysed by means of stepwise logistic regression and calculation of adjusted relative risks. Subjects:In the investigation in 1988/89, 12901 people above 16 years of age participated and the response rate was 80%. Results:In comparison between the investigations, the prevalence of reported impairment was lower in 1988/89 than in 1975 and 1980/81. Prevalence of reported impairment of chewing ability increased with ageing from 2% in young adults (16–34 years old) to 44% in older elderly (〉85 years old). In most age groups, edentulous people reported the highest prevalence, and dentate people the lowest. Relative risks for impaired masticatory ability, independent of age, gender and dental state, were higher for people in rural areas, with low income and living single, as well as for those with skeletal, gastrointestinal, psychiatric and tumour diseases. In the elderly, results from the logistic regression showed that some disability and psychosocial factors were also associated with masticatory ability. Conclusions: The results indicated that there was a group of elderly people who reported several functional and health problems including impaired masticatory ability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1741-2358.1996.tb00162.x
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