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  • 1
    Electronic Resource
    Electronic Resource
    Fact, fiction and fraud (1976)
    [s.l.] : Nature Publishing Group
    Nature 264 (1976), S. 126-127 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN this book Joseph Hixson tells the story of Dr William Summerlin, and much more besides. Summerlin, a dermatologist turned immunologist, claimed that tissue which had been kept in culture could be grafted across transplantation, even species, barriers. But, in 1974, when working at the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/264126b0
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  • 2
    Electronic Resource
    Electronic Resource
    Limits to oncology (1975)
    [s.l.] : Nature Publishing Group
    Nature 254 (1975), S. 547-548 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] EVEN in these hard times, the -*-/ support available for cancer re-search is relatively large by comparison with other biomedical fields, especially in the USA. But, in spite of clear enough aims in terms of alleviation of suffering caused by cancer, the course to be followed is uncharted and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/254547a0
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  • 3
    Electronic Resource
    Electronic Resource
    Abortive Transformation by Polyoma Virus (1968)
    [s.l.] : Nature Publishing Group
    Nature 218 (1968), S. 234-238 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Exposure of hamster cells to large doses of polyoma virus is known to result in permanent transformation of a small proportion of cells. Experiments with cells in suspension now suggest that a much higher proportion of infected cells undergoes a temporary change, in which at least one ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/218234a0
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  • 4
    Electronic Resource
    Electronic Resource
    Effect of X-Irradiation on Susceptibility of Cells to Transformation by Polyoma Virus (1963)
    [s.l.] : Nature Publishing Group
    Nature 200 (1963), S. 756-758 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE ability of polyoma virus to alter the hereditary properties of cells (polyoma transformation)1'2 can be estimated quantitatively in vitro using the BHK21 line of hamster fibroblasts3'4, and investigations can now be made on the conditions which affect the frequency of transformation following ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/200756a0
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  • 5
    Electronic Resource
    Electronic Resource
    Multiplication of Solitary HeLa Cells (1958)
    [s.l.] : Nature Publishing Group
    Nature 181 (1958), S. 1407-1408 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The method we have used is based on the technique developed by de Fonbrune1 in which cells were isolated in small droplets of culture medium under paraffin oil. This method was employed by Lwoff et l.2 for the study of virus release from single HeLa cells, but the uninfected cells failed to divide ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1811407a0
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  • 6
    Electronic Resource
    Electronic Resource
    Hepatocytes and scatter factor (1990)
    [s.l.] : Nature Publishing Group
    Nature 346 (1990), S. 228-228 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] SIR-Scatter factor, a cytokine secreted by certain fibroblasts, enhances the movement and causes the dissociation and scattering of epithelial cells1'3, and may be involved in epithelial migration, for example in embryogenesis2. Mouse scatter factor has an apparent relative molecular mass of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/346228b0
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  • 7
    Electronic Resource
    Electronic Resource
    Scatter factor is a fibroblast-derived modulator of epithelial cell mobility (1987)
    [s.l.] : Nature Publishing Group
    Nature 327 (1987), S. 239-242 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The scattering activity released into culture medium by the MRC5 strain of human fibroblasts was originally observed in human mammary epithelial cells1'2. Subsequently the Madin Darby canine kidney (MDCK) cell line was also found to be highly sensitive, and suitable for assay of activity by ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/327239a0
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  • 8
    Electronic Resource
    Electronic Resource
    Molecular dirty tricks ban (1974)
    [s.l.] : Nature Publishing Group
    Nature 250 (1974), S. 278-278 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE critics of molecular biology are fond of pointing out the scarcity of practical benefits. It is a sad paradox that the very developments which could ultimately have immense value for production of useful, but rare, molecules, should result in an urgent cry of 'halt' from a committee of leading ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/250278c0
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  • 9
    Electronic Resource
    Electronic Resource
    Abortive Transformation by the Tsa Mutant of Polyoma Virus (1969)
    [s.l.] : Nature Publishing Group
    Nature 223 (1969), S. 397-398 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] When hamster cells of the BHK21 line are exposed to polyoma virus at sufficiently high multiplicities, a large proportion of cells develop a characteristic of transformed cells, namely the ability to grow in suspension. In most of the transformed clones, however, this altered growth character is ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/223397a0
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  • 10
    Electronic Resource
    Electronic Resource
    Syrian Hamster Fibroblast Cell Line BHK 21 and its Derivatives (1964)
    [s.l.] : Nature Publishing Group
    Nature 203 (1964), S. 1355-1357 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THE BHK2I line of diploid hamster fibroblasts is J. used widely for research on viruses and on neoplastic transformation. The purpose of this article is to describe the origin of the cells, to list viruses to which they are susceptible, and to summarize the main characteristics of some variants of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2031355a0
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