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  • 1
    Electronic Resource
    Electronic Resource
    Reversible G2/M blockade of an hybridoma cell line by the colchicine analog MTC
    Amsterdam : Elsevier
    Biology of the Cell 73 (1991), S. 43 
    Details
    ISSN: 0248-4900
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0248-4900(91)90237-H
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  • 2
    Electronic Resource
    Electronic Resource
    ELECTROCHEMICAL PROPERTIES OF PLATELETS: CLINICAL AND PHARMACOLOGICAL APPLICATIONS (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 416 (1983), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1983.tb35223.x
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  • 3
    Electronic Resource
    Electronic Resource
    Dye-affinity purification of transthyretin from an unexploited by-product of human plasma chromatographic fractionation
    Amsterdam : Elsevier
    Journal of Chromatography B: Biomedical Sciences and Applications 576 (1992), S. 87-93 
    Details
    ISSN: 0378-4347
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0378-4347(92)80178-S
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  • 4
    Electronic Resource
    Electronic Resource
    Analytical study of ionized or ionizable groups of platelet membrane (1979)
    Springer
    Annals of hematology 38 (1979), S. 103-117 
    Details
    ISSN: 1432-0584
    Keywords: Plättchenmembran ; Carboxyl-Gruppen ; SH ; Amino-Gruppen ; Phosphat-Gruppen ; Platelet membrane ; Carboxyl groups ; SH ; Amino groups ; Phosphate groups
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The knowledge of the molecular surface groups of the human blood platelets present a particular interest especially in some thrombotic processes or thrombocytopathies. The aim of this study was to approach quantitatively ionized or ionizable groups of the platelet membrane using liquid phase electrophoresis or physicochemical and analytical methods with specific reagents. A mean repartition of the principal groups (carboxyl, SH, amino and phosphate) on the membrane is obtained by cell electrophoresis.
    Notes: Zusammenfassung Die Kenntnis der molekularen Oberflächengruppen der menschlichen Blutplättchen ist von besonderem Interesse, vor allem bei thrombosenbezüglichen Prozessen und Thrombozytopathien. Das Ziel dieser Untersuchung war es, ionisierte oder ionisierbare Gruppen der Plättchen-Membran quantitativ zu erfassen unter Anwendung von liquider Phasenelektrophorese oder physikalisch-chemischen und analytischen Methoden unter Anwendung spezieller Reagensmittel. Eine gleichmäßige Verteilung der Hauptgruppen (Carboxyl, SH, Amino und Phosphat) auf der Membran wird durch Zellelektrophorese erzielt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01007951
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  • 5
    Electronic Resource
    Electronic Resource
    Action de deux polybases sur la charge et l'agrégation des plaquettes (1972)
    Springer
    Cellular and molecular life sciences 28 (1972), S. 1096-1097 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The action of two polybases (polybren and DEAE Dextran) on the electrophoretic mobility of platelets is studied. These two substances induce a decrease of the mobility. An investigation of the aggregability with the help of a photometric test shows a correlation between the charge decrease and platelet aggregation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01918696
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  • 6
    Electronic Resource
    Electronic Resource
    Time-dependent formation of red blood cell aggregates and its influence on blood rheological behaviour (1993)
    Springer
    Journal of biological physics 19 (1993), S. 65-70 
    Details
    ISSN: 1573-0689
    Keywords: Red blood cells ; kinetics of RBC aggregation ; blood rheology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The aggregation of red blood cells (RBC) is a time-dependent process measured clinically for the assessment of possible pathological changes in diseases. In this paper, a quantitative description of the process is suggested to provide the basis for the quantification of their measurement. In addition, the rheological aspect of RBC aggregation is analyzed with the aim of specifying the effect of the mechanism of RBC aggregation on blood rheological behaviour characterized by shear thinning, thixotropy, and viscoelasticity. Rheological predictions are compared with data for time-dependent blood viscosity changes after a sudden stop and sudden increase of shearing.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00700130
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  • 7
    Electronic Resource
    Electronic Resource
    Potential interest of optical fibres as immunosensors: study of different antigen coupling methods (1991)
    Springer
    Journal of materials science 2 (1991), S. 197-201 
    Details
    ISSN: 1573-4838
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract New approaches in the field of fluoroimmunoassays involve the use of optical fibres as solid support of reagents and waveguide. Parameters which influence the response of optical fibre fluoroimmunosensors have been studied. Several methods, involving either a physical or a covalent process, have been investigated for immobilizing on silica surfaces polyclonal rabbit immunoglobulin (IgG) as antigen. Fluorescent anti-rabbit IgG has been used for determining immobilized antigen levels. The fluorescence intensity emitted by the immunosensors has been determined by using the evanescent wave phenomenon. The binding capacity of the different immunosensors tested appears nearly similar, except for the sensor prepared with the 3-glycidoxypropyl trimethoxysilane coupling method which seems to exhibit a lower binding capacity. For all sensors prepared with a covalent coupling method, a simultaneous adsorption phenomenon probably affects the long-term stability of immunosensors. In a further step, the possibility of immunosensor regeneration after a dissociation of antigen/antibody complexes has been tested. It appears that the dissociation methods could affect the sensor response. Finally, the specificity of immunosensors has been investigated. A significant cross reactivity was observed forp-toluenesulphonyl chloride and 3-aminopropyl triethoxysilane (APTES)-derivatized fibres. For the APTES-derivatized sensor, the specificity markedly decreased after a dissociation step. Therefore, although the feasibility of a competitive assay has been established, suitable conditions of immunosensor regeneration still require further investigation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00703369
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  • 8
    Electronic Resource
    Electronic Resource
    Effect of Fibrin Polymerzation on Flow Properties of Coagulating Blood (1997)
    Springer
    Journal of biological physics 23 (1997), S. 121-128 
    Details
    ISSN: 1573-0689
    Keywords: Blood coagulation ; Fibrin Polymerization ; Blood rheology.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The evolution of stress in coagulating blood is described by aMaxwell-like constitutive model. The evolution is essentiallyaffected by conversion of fibrinogen to fibrin monomer, fibrinpolymerization and its crosslinking. The modifying effects of theprocess result from the active constituents of blood plasma,blood cell concentration and intensity of flow. Interrelationof stress evolution and the kinetics of polymerization species these effects in terms of the order of the kinetics ofpolymerization and degree of fibrin polymerization and values of the constitutive coefficients. The results are presented for a normal blood, averaging the effect of blood constituents and blood platelets on coagulation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1004973427458
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  • 9
    Electronic Resource
    Electronic Resource
    Three-Dimensional Fluorescence Microscopy of Endothelial Cells Labeled with Coumarins (2000)
    Springer
    Journal of fluorescence 10 (2000), S. 203-203 
    Details
    ISSN: 1573-4994
    Keywords: Coumarin tracers ; three-dimensional microscopy ; endothelial cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Fluorescent coumarins were synthesized with the objective of introducing a glucosamine part in the chemical structure, with either hydroxyl or acetyl functions. The photophysical behavior was studied in organic solvents with different polarity and viscosity. The location of the fluorescent coumarins in endothelial cells was studied using fluorescence microscopy imaging, especially with a 3-D CELLscan instrument.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1009407512674
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  • 10
    Electronic Resource
    Electronic Resource
    Transient rheology in a new type of couette apparatus. Application to blood (1989)
    Springer
    Rheologica acta 28 (1989), S. 423-434 
    Details
    ISSN: 1435-1528
    Keywords: Couette viscometer ; transientflow ; bloodrheology ; red cell deformability
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Abstract By using our new air-bearing viscometer different types of transient flow can be studied; in the present work this viscometer was specifically applied to non-Newtonian blood suspensions. To observe the influence of both the aggregation and the deformation of red blood cells (RBCs), different concentrations of fibrinogen and dextran were used: the suspended RBCs were simply washed or rigidified with diamide. From the data three rheological parameters were determined, two of which are relative to the behavior at low and at high shear gradients, respectively. Their values were related to the theory of Taylor, and the internal viscosity of RBCs was estimated to be around 3 cp.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01336810
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