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  • 1
    ISSN: 1523-5378
    Quelle: Blackwell Publishing Journal Backfiles 1879-2005
    Thema: Medizin
    Notizen: Since the bacterium H. pylori was identified in 1982, overwhelming evidence has implicated it as the causal factor in the occurrence and relapse of peptic ulcer disease. The major objective of this study was to examine the extent to which physicians recognize H. pylori as a causal agent in peptic ulcer disease or as potential cofactor in other gastrointestinal diseases, and the extent to which this knowledge has influenced diagnostic and therapeutic practices.〈section xml:id="abs1-2"〉〈title type="main"〉Materials and Methods.Using a national mail survey in Germany in September 1995, 1197 family practitioners and 1197 gastroenterologists were selected for the study.〈section xml:id="abs1-3"〉〈title type="main"〉Results.Of the surveyed physicians, 756 (32%) responded. Family practitioners treated almost 50% of their patients with initial presentation of suspected ulcer disease without ordering further diagnostic tests. More than 25% of the family practitioners and 14% of the gastroenterologists reported that they do not treat diagnosed H. pylori infection in the first presentation of duodenal ulcer. At the time we conducted the study, 22% of responding family practitioners and 5% of responding gastroenterologists treated the first presentation of H. pylori-positive ulcer disease with regimens determined to be ineffective according to the available literature.〈section xml:id="abs1-4"〉〈title type="main"〉Conclusions.Gastroenterologists preferred to treat H. pylori infection when the associated disease was one for which a causal relationship had been more clearly established, while family practitioners showed less discrimination. In order to provide optimal therapy aimed at minimizing the course and consequences of H. pylori-related diseases, researchers in the field must ensure continuous dissemination of current knowledge.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 1432-1459
    Schlagwort(e): Transcranial magnetic stimulation ; Short-term memory ; Corsi-Block test ; Digit-Span test
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The effect of rapid-repetitive transcranial magnetic stimulation (rr-TMS) on the immediate verbal and visuospatial memory span was assessed by computerized neuropsychological testing in 11 healthy volunteers. The objective was to test whether rr-TMS may be utilized as a non-invasive tool for evaluation of memory function. The subjects had to memorize series of numbers (Digit-Span test) or the position of cubes (Corsi-Block test) shown to them on a computer screen and actively reproduce them immediately after the presentation. Synchronous with the appearance of each item an rr-TMS train of 550 ms duration was delivered to the left or right anterolateral parietal as well as superior and posterior lateral temporal region at 50 Hz and with approximately 1.0 T stimulation intensity. Statistical comparison of memory performance during rr-TMS and baseline testings without stimulation revealed no significant changes. No adverse effects were observed. Thus, rr-TMS does not affect short-term memory performance in healthy individuals under the stimulation conditions described above.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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