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  • 1
    Electronic Resource
    Electronic Resource
    5-Hydroxytryptamine and punishment (1977)
    [s.l.] : Nature Publishing Group
    Nature 268 (1977), S. 741-743 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] If a response is followed by punishment, the probability of its occurrence decreases. 5-HT antagonists1"3 and synthesis inhibition4'6 have been shown to re-instate rates of punished responding. Furthermore, behavioural release following synthesis inhibition has been shown to correlate closely with ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/268741a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Some behavioural signs of morphine withdrawal blocked by conditional stimuli (1975)
    [s.l.] : Nature Publishing Group
    Nature 255 (1975), S. 416-418 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] This theory is receiving support from experimental studies on animals. In rats2 and monkeys3, it has 'been shown that conditional stimuli previously associated with the withdrawal of a drug can elicit physiological disturbances characteristic of withdrawal. In contrast, they may also serve to ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/255416a0
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Differential enhancement of locomotor activity by dopamine agonists following chronic morphine treatment (1979)
    Springer
    Psychopharmacology 63 (1979), S. 313-315 
    Details
    ISSN: 1432-2072
    Keywords: Locomotor activity ; Di-isobutyryl apomorphine ; Lergotrile ; Morphine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Animals were administered increasing doses of morphine for 16 days. During withdrawal they were challenged with an apomorphine ester or lergotrile. These dopamine agonists produced quantitatively different effects on behaviour. The results suggest that chronic morphine administration leads to dopamine supersensitivity which may be anatomically distinct in origin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00433570
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Chlordiazepoxide and isolation induced timidity in rats (1975)
    Springer
    Psychopharmacology 44 (1975), S. 83-85 
    Details
    ISSN: 1432-2072
    Keywords: Isolation ; Chlordiazepoxide ; Emergence ; Rats
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of chlordiazepoxide (CDP) on emergence behavior was examined in socially reared and isolation reared rats. It was found that low doses of CDP decreased the emergence times of isolated animals but had little effect on the emergence of social animals. At higher doses the drug retarded emergence in all groups but there were no differential effects. The results do not support claims that rearing conditions influence the susceptability of rats to CNS depressants, rather they suggest that particular levels of CDP selectively influence “emotional” behavior.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00421188
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Benzodiazepines and discrimination behaviour: Dissociation of response and sensory factors (1977)
    Springer
    Psychopharmacology 52 (1977), S. 191-194 
    Details
    ISSN: 1432-2072
    Keywords: Conditional discrimination ; Fixed interval ; Chlordiazepoxide ; Flurazepam ; Sensory effects ; Motor effects ; Pigeons
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Ten London pigeons were trained on a schedule which allowed concurrent measurement of motor and exteroceptive sensory changes. The task involved a conditional colour discrimination contingent upon the completion of a fixed interval schedule of responding. As a preliminary pharmacological study the effects of the benzodiazepines, chlordiazepoxide and flurazepam were investigated. Both drugs enhanced perseverative responding (after completion of the FI), and to a variable degree responding during the FI, although there was no evidence for an increase in responding during the inter-trial-intervals. On the other hand, no marked changes in discrimination performance were observed. It is concluded that the most significant effects of these benzodiazepines are on motor mechanisms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00439109
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    Paper (German National Licenses)
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