ISSN:
1432-086X
Keywords:
Liver
;
Hepatocellular carcinoma
;
Transcatheter arterial embolization
;
Lipiodol
;
Gel
;
foam sponge
;
Cox's proportional hazard model
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Purpose Multivariate analysis was used to study the effectiveness and optimum dose level of Lipiodol (LP) in transcatheter arterial embolization (TAE) of hepatocellular carcinoma (HCC). Methods A total of 219 cases of nodular type HCC, with a tumor diameter less than 7 cm, were studied. TAE was performed using both Gelfoam sponge (GS) and LP in 158 cases; in the remaining 61 cases only GS was used. Results Statistical stepwise variable selection revealed that only LP had a negative T-value, suggesting that LP is a useful factor for prognosis. The most favorable effect on patient prognosis was obtained with an LP dose level (expressed in mm) of 1–1.5 times the absolute value of the tumor diameter (expressed in cm). Conclusion A significant difference (p 〈 0.01, logrank test) in survival was found between the GS with LP group and the GS only group, using Cox's proportional hazard model.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00193921
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