Electronic Resource
Oxford, UK
:
Blackwell Publishing Ltd
Journal of neurochemistry
16 (1969), S. 0
ISSN:
1471-4159
Source:
Blackwell Publishing Journal Backfiles 1879-2005
Topics:
Medicine
Notes:
Abstract— 〈list xml:id="l1" style="custom"〉1The bound ACh of rabbit brain tissue homogenate was studied with the French press technique by means of which nerve endings can be ruptured under isotonic condition.2Two fractions of B-ACh, stable and labile were obtained which were roughly equal in amount. The yield of B-ACh after disruption of nerve ending particles was about 28 per cent of the initial total ACh and higher than that formed after the hypotonic disruption.3The results support the view that the stable fraction of B-ACh is enclosed inside the vesicle membrane, while the labile fraction is present in the cytoplasm of the cell.4ACh released from such intact vesicle fractions was roughly parallel to the ionic strength of the solution at 0°, without relation to the nature of the ion itself.5Electronmicroscopic examination with PTA showed that the vesicles released by the French press technique were largely intact, although the nerve ending particles were completely disrupted by the same treatment.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1111/j.1471-4159.1969.tb10342.x
Permalink
Library |
Location |
Call Number |
Volume/Issue/Year |
Availability |