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  • 1
    Electronic Resource
    Electronic Resource
    Cytotoxicity of Various Calcium Phosphate Ceramics (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 309-311 (May 2006), p. 263-266 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The cytotoxicity of five calcium phosphate ceramics, hydroxyapatite (HAp),flouroapatite (FAp), α-tricalcium phosphate (α-TCP), β-tricalcium phosphate (β-TCP) and tetracalcium phosphate (TTCP), was investigated. Based on the guidelines of biological test for medical devices in Japan, a cytotoxicity test of these calcium phosphates was carried out using Chinese hamster V79 lung fibroblasts. The cytotoxic study revealed that FAp and α-TCP showed high cytotoxicities. From various analyses, it was considered that the cytotoxicity of the FAp wasdue to fluorine ions extracted in a culture medium and the cytotoxicity of α-TCP resulted from a decrease in pH of the medium by the phosphoric acid, which produced by hydrolysis of( the α-TCP
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/50/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.309-311.263.pdf
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  • 2
    Electronic Resource
    Electronic Resource
    Novel Calcium Phosphate Ceramics: The Remarkable Promoting Action on the Differentiation of the Normal Human Osteoblasts (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 309-311 (May 2006), p. 97-100 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: To promote the activity of normal human osteoblasts (NHOst), the novel HAp ceramics containing Nb ions (NbHAp) were synthesized by wet chemical process, which reacting aqueous solution containing a mixture of Ca(NO3)2, (NH4)2HPO4, and the Nb aqueous solution. X-ray diffractionpatterns indicated that NbHAp had a monolithic apatitic structure, although crystallite decreased as Nb content increased. From inductively coupled plasma analysis, maximum amount of Nb ions in the sample was almost 8.2atom% of P ions. The NbHAps were presented as aggregates and composed of fine crystal of 〈1µm in diameter. Nb ions in NbHAp were uniformly distributed in the aggregates. Furthermore, high-resolution XPS spectra of Nb 3d5/2 indicated that Nb ions in theHAp were presented as Nb5+. These results suggested that Nb ions were at PO4 site in crystal structure of HAp. When NHOst were cultured with the NbHAp, their ALP activity were twice as much as that of NHOst cultured with HAp without Nb ions
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/50/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.309-311.97.pdf
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  • 3
    Electronic Resource
    Electronic Resource
    Transmission Electron Microscopic Study on Thermal Decomposition Process of Calcium-Deficient Hydroxyapatite (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 317-318 (Aug. 2006), p. 785-788 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In our previous study, we reported that a metastable phase with high Ca/P molar ratioappeared in the temperature range from 700 οC to 800οC[removed info] The purpose of this study is to investigatethe crystallographic relationship between the metastable phase and HAp matrix. Ca-def HAp wasannealed at 500-1000' ο C in air. High-resolution transmission electron microscopic (HRTEM)observations were performed along the [010], [110] and [001] zone axes in order to investigate thestructure of the metastable phase. From HRTEM images and results of the analysis of selected areaelectron diffraction patterns along [010], [110] and [001] zone axes, the lattice constants of themetastable phase were analyzed into a=2.86nm, b=0.94nm, and c=0.69nm of an orthorhombiccrystals system
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/51/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.317-318.785.pdf
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    Paper (German National Licenses)
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