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  • 1
    Electronic Resource
    Electronic Resource
    The C-Propeptide of Type II Procollagen Binds to the Enhancer Region of the Type II Procollagen Gene and Regulates its Transcription (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 785 (1996), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1996.tb56292.x
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  • 2
    Electronic Resource
    Electronic Resource
    Structural Change Caused by Substitution of Nd for Sm in (Nd, Sm)AlO3: Application of Synchrotron High-Resolution Powder X-ray Diffraction (1998)
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 31 (1998), S. 663-671 
    Details
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: Structural change caused by substitution of Nd for Sm in perovskite (Nd, Sm)AlO3 was analysed by application of high-resolution powder X-ray diffraction using synchrotron radiation. The parallel, well monochromated and bright incident X-rays improved the full width at half-maximum (FWHM) to 0.027° in a wide 2θ range for the standard Si powder. Applying this high-resolution optical system, the lattice parameters of the solid solution (Ndx, Sm_{1-x})AlO3 were precisely analysed for the phases from x = 0.0 to 1.0 with an interval of 0.2. The lattice parameters of a series of RAlO3 vary systematically with the average ionic radii of R^{3+}, accompanying a structural change from orthorhombic to a trigonal system at around R^{3+}=1.11 Å corresponding to average ionic radii of 0.7{\rm Nd}^{3+}+0.3{\rm Sm}^{3+}. In orthorhombic phases, deformation of the crystal lattice from its ideal cubic lattice is minimized at around x = 0.0–0.2 in (Ndx, Sm_{1-x})AlO3 and increased with increasing average ionic radii of Nd^{3+} and Sm^{3+}. The structure changes from orthorhombic to trigonal at around x = 0.7.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0021889898001629
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  • 3
    Electronic Resource
    Electronic Resource
    Enhancement in the perfection of orthorhombic lysozyme crystals grown in a high magnetic field (10 T) (2000)
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 56 (2000), S. 1079-1083 
    Details
    ISSN: 1399-0047
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Orthorhombic crystals of hen egg-white (HEW) lysozyme were grown in a homogeneous and static magnetic field of 10 T. All crystals grown at 10 T were oriented such that their crystallographic c axes were parallel to the magnetic field direction and showed a narrower average full-width at half-maximum (FWHM) of the rocking curve than those grown at 0 T. Rocking-width measurements were made at the BL-10A station at the Photon Factory, Tsukuba, Japan, using a high-resolution vertical-type four-circle diffractometer. Crystal perfection was evaluated using the FWHM of the rocking curve; the effects of the magnetic field on the quality of the crystals were examined by comparison of the FWHM of seven crystals grown at 10 and 0 T. The FWHMs of the reflections along the a, b and c axes decreased by 23.5, 35.3 and 27.8%, respectively, and those of other general reflections decreased by 17.4–42.2% in the crystals grown at high magnetic field. These results clearly showed that a magnetic field of 10 T improved the crystal perfection of the orthorhombic lysozyme crystals. As a result, the maximum resolution of X-ray diffraction increased from 1.3 Å at 0 T to 1.13 Å at 10 T. The magnetic field also affected the dimensions of the unit cell, increments being 0.2% for the a and c axes and 0.1% for the b axis, respectively. These facts suggest that the application of a high magnetic field during crystallization might result in remarkable enhancements in the diffraction power of protein crystals having magnetic anisotropy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0907444900008155
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  • 4
    Electronic Resource
    Electronic Resource
    DAFS measurements using the image-plate Weissenberg method (1998)
    Chester : International Union of Crystallography (IUCr)
    Journal of synchrotron radiation 5 (1998), S. 908-910 
    Details
    ISSN: 1600-5775
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: An instrumental technique for DAFS measurements which can provide site-specific information is proposed. The approach uses (i) focusing optics with parabolic mirrors and a double-crystal monochromator, (ii) the Laue and Bragg settings and (iii) data collection by the image-plate Weissenberg method. Six image exposures are recorded per plate at five intrinsic energies and one reference energy. The single-crystal measurements were performed at the Co K-absorption edge, and the 200, 220 and 311 reflections of CoO and 511 and 911 reflections of Co3O4 were used for analysis. The regression analysis of χ(k), Fourier transforms of k3χ(k) and back-Fourier filtering have been performed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0909049598000594
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  • 5
    Electronic Resource
    Electronic Resource
    Characterization of Thin Polymer Films by X-ray Reflectometry with Synchrotron Radiation (1998)
    Chester : International Union of Crystallography (IUCr)
    Journal of synchrotron radiation 5 (1998), S. 1304-1308 
    Details
    ISSN: 1600-5775
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: X-ray reflectivity (XR) measurements with a synchrotron radiation source were carried out for thin polymer films on a glass plate. From the XR data, the film thickness and surface and interface roughnesses could be determined. In addition, the appropriate conditions and precision for measurements were also discussed. Kiessig fringes were observed clearly for specular XR measurements of poly(methylmethacrylate) thin film. Analysis of the XR data allowed the determination of the film thickness very precisely. By a curve-fitting procedure of the XR profile, the film-surface roughness and film–substrate interface roughnesses were determined. A Fourier transform of the XR data was performed as an alternative method of evaluating the film thickness. The values for the film thickness obtained by the curve-fitting procedure and Fourier-transform procedure were slightly different from each other. One possibility for the cause of this difference may be an integral error and/or cut-off effect in the Fourier-transform procedure. The XR technique with synchrotron radiation is a very powerful tool for structural characterization of thin polymer films.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0909049598006797
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  • 6
    Electronic Resource
    Electronic Resource
    Lobeline production by hairy root culture of Lobelia inflata L. (1990)
    Springer
    Plant cell reports 9 (1990), S. 307-310 
    Details
    ISSN: 1432-203X
    Keywords: Lobelia inflata L. ; hairy root ; lobeline ; root morphology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Hairy roots were obtained following inoculation of the stems of Lobelia inflata L. with Agrobacterium rhizogenes strain ATCC 15834. These hairy roots contained agropine and mannopine. In addition, lobeline was detected by HPLC and confirmed by mass spectrometry. Various media were tested for the growth of hairy roots as well as for the content of lobeline in hairy roots. The growth rate of hairy roots cultured in Nitsch and Nitsch's medium was approximately one third of those cultured in other media. The lobeline content of hairy roots (18–54 μg/g dry weight) cultured in these media was the same order of magnitude compared with that of roots of L. inflata (24 μg/g dry weight) cultivated in pots. The hairy roots cultured in Nitsch and Nitsch's medium were morphologically different from those cultured in other media.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00232857
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  • 7
    Electronic Resource
    Electronic Resource
    An experimental study of gastric mucosal blood flow in endotoxemia of the rat, with special reference to the vagus nerve and EDRF (1995)
    Springer
    Journal of gastroenterology 30 (1995), S. 8-15 
    Details
    ISSN: 1435-5922
    Keywords: endotoxin ; endothelial-derived relaxing factor (EDRF) ; gastric mucosal blood flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Gastric mucosal lesions are an important complication in endotoxemia. In order to define the role played by the vagus nerve and endothelial-derived relaxing factor (EDRF) in gastric mucosal blood flow, an investigation was carried out on four groups of rats: a control group; a group given lipopolysaccharide (LPS, 5 mg/kg); a group given gossypol-acetic acid (gossypol), which has an injurious effect on the vascular endothelial cell; and a group given L-NG-monomethyl arginine (LNMMA). Following the administration of acetylcholine and papaverine hydrochloride (via the splenic artery) and vagus nerve stimulation in all four groups of rats, the effects of vagus nerve stimulation and EDRF on the gastric mucosal blood flow were determined with a laser Doppler rheometer. In the LPS group, the gastric mucosal blood flow was decreased after acetylcholine administration and vagus nerve stimulation. This was also the case in the gossypol group. These findings suggest that inhibition of EDRF release may be responsible for the reduced gastric mucosal blood flow observed in endotoxemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01211368
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  • 8
    Electronic Resource
    Electronic Resource
    A case of endolymphatic sac tumor with long-term survival (1999)
    Springer
    Brain tumor pathology 16 (1999), S. 69-76 
    Details
    ISSN: 1861-387X
    Keywords: Endolymphatic sac tumor ; Adenoma ; Papillary structure ; Immunohistochemistry ; Long-term survival
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A 72-year-old man developed left facial palsy at age 14 and left-sided hearing loss at age 20. At the age of 59, he presented with gait disturbance, and a large left cerebellopontine angle tumor was detected, which had markedly destroyed the pyramidal bone. The tumor was subtotally resected, but he required two more operations at the ages of 64 and 69 because of tumor regrowth. At the present time, recurrent tumor has destroyed the occipital bone and is invading the scalp. However, eventhough he has several cranial nerve palsies and cerebellar ataxia, he remains in stable condition and demonstrates long-term survival. The patient's surgical specimens revealed a papillary adenoma, which was recently thought to be of endolymphatic sac origin, although the origin of this kind of tumor, whether arising from the middle ear or from the endolymphatic sac, has not been established with certainty so far. In this paper, we provide further evidence that this tumor originates from the endolymphatic sac, based on anatomical, histopathological, and embryological evidence.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02478905
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  • 9
    Electronic Resource
    Electronic Resource
    Role of 123I-IMP SPET in the early diagnosis of borderline chronic hydrocephalus after aneurysmal subarachnoid haemorrhage (2000)
    Springer
    European journal of nuclear medicine 27 (2000), S. 559-565 
    Details
    ISSN: 1619-7089
    Keywords: Key words: Subarachnoid haemorrhage – Iodine-123 labelled N-isopropyl-p-iodoamphetamine – Single-photon emission tomography – Hydrocephalus – Cerebral blood flow
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Chronic hydrocephalus after aneurysmal subarachnoid haemorrhage (SAH) is easily diagnosed in most cases. However, the diagnosis is sometimes difficult in borderline cases, in which (a) pathognomonic clinical deterioration due to hydrocephalus is masked by the neurological deficits caused in the acute stage of SAH and (b) ventricular enlargement is not so marked on CT scan. The purpose of this study was to investigate whether or not iodine-123 labelled N-isopropyl-p-iodoamphetamine (123I-IMP) single-photon emission tomography (SPET) is of value for the early diagnosis of borderline chronic hydrocephalus after SAH. Fifteen patients who met the criteria of borderline chronic hydrocephalus were selected for the study, and underwent a shunt operation. The patients were divided into a shunt-effective group and a shunt-ineffective group according to neurological improvement after the shunt operation. 123I-IMP SPET was performed in the acute stage of SAH, within 1 week before the shunt operation, and 2 weeks after the shunt operation. Regional cerebral blood flow was estimated by the 123I-IMP autoradiographic method. Pre-shunting periventricular low-perfusion areas showed statistically significant differences between the two groups (P〈0.05). In the shunt-effective group, periventricular low-perfusion areas on pre-shunting SPET were significantly enlarged compared with those in the acute stage of SAH (P〈0.05), and they were significantly reduced after the shunt operation (P〈0.05). In the shunt-ineffective group, periventricular low-perfusion areas showed no significant changes during the course. These results suggest that periventricular low-perfusion areas enlarge in the early stage of chronic hydrocephalus after SAH, and that 123I-IMP SPET can be used for both the early diagnosis of borderline chronic hydrocephalus after SAH and the prediction of shunt effectiveness.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002590050543
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