ISSN:
1437-160X
Keywords:
Yersinia
;
Salmonella
;
Campylobacter
;
Borrelia
;
Antibodies
;
ELISA
;
Arthritis
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary IgM, IgG and IgA class antibodies againstYersinia, Salmonella, Campylobacter andBorrelia were determined by enzyme-linked immunosorbent assay (ELISA) in a group of 340 unselected patients with a recent inflammatory joint disease. The control group consisted of 340 and 100 healthy blood donors usingBorrelia-ELISA and other ELISAs, respectively. Of all the patients, 27.4% had increased antibody levels against at least one of the microbes tested. The prevalence of positive antibody levels was highest inYersinia antibodies (17.9%). The corresponding figures forSalmonella, Campylobacter andBorrelia were 7.0, 6.2 and 1.8%, respectively. Patients with entero-arthritis or clinically typical reactive arthritis who had not had gastrointestinal or urogenital symptoms previously had the highest prevalence of the microbial antibodies (67.6 and 40.7%, respectively). These findings indicate that arthritis may often have a reactive etiopathogenesis without recognized gastrointestinal infection, emphasizing the importance of microbial serology in the differential diagnosis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02274884
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