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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anatomia, histologia, embryologia 26 (1997), S. 0 
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In this study, the development of myelination in the fetal bovine brain (age-range: between 1–2 and 8–9 months) was examined applying: 1. Immunohistochemical staining methods and antibodies against bovine proteolipid protein (PLP), synthetic tridecapeptide of bovine PLP, human myelin basic protein (MBP), human myelin-associated glycoprotein (MAG); and 2. Using the Luxol fast-blue (LFB) technique.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anatomia, histologia, embryologia 23 (1994), S. 0 
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: In the present immunohistochemical study, the distribution and differentiation of glial and neuronal cells in bovine fetal brains (age range: between1–2 and7–8 months) was examined using antibodies against nervous system-specific proteins, i. e., glial fibrillary acidic protein (GFAP), vimentin, neuron specific enolase (NSE) and a neurofilament protein subunit (NF 200 kD).
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Anatomia, histologia, embryologia 27 (1998), S. 0 
    ISSN: 1439-0264
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The distribution of transferrin in brains from fetuses (age-range: 1–2 to 8–9 months of gestational age), calves, subadult (between 1 day and 9 months old) and adult cattle (〉12 months old) were examined by immunohistochemistry. In both pre- and postnatal brains transferrin was predominantly found in oligodendrocytes. Furthermore, transferrin immunostaining was present in single to few neurons, within the lumina of vessels, in endothelial cells, in epithelial cells of the choroid plexus and in ependymal cells. A caudorostral progress in the appearance of transferrinpositive cells was found. In fetuses, transferrinpositive mature oligodendrocytes and neurons were not detected before 3–4 months of gestational age. Findings in different brain areas of older fetuses suggest an association between the increase of transferrin-positive oligodendrocytes and the process of myelination. In brains from calves and subadult cattle a continuous decrease of transferrin-immunoreactive oligodendrocytes and neurons was noted.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-0533
    Keywords: Key words: Bovine virus diarrhoea virus – Porencephaly – Hydranencephaly – Ovine fetuses – Antigen distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. The distribution of viral antigen, histological lesions and inflammatory responses were examined in brains from ovine fetuses following experimental transplacental infection with a cytopathogenic strain of bovine virus diarrhoea virus (BVDV). At 10 and 14 days post inoculation (p.i.) viral antigen-containing cells were found throughout the different zones of the developing telencephalon and cerebellum. Corresponding to the distribution of viral antigen, necrotic lesions both of already differentiated and of undifferentiated fetal brain cells occurred. The extent and severity of microscopic lesions correlated positively with the number of viral antigen-containing cells. The destructive lesions were accompanied by meningeal and parenchymal cellular infiltrations predominantly with phagocytosing macrophages. In fetuses examined at 21 days p.i. a massive necrosis of the cerebral hemispheres and severe infiltrations with macrophages and CD3-positive lymphocytes had developed. In fetuses studied between 32 and 80 days p.i. porencephaly, hydranencephaly and leukoencephalomalacic lesions were present. In brain tissue of these fetuses, with the exception of two cases, BVD viral antigen was no longer detected.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 42 (1986), S. 999-1001 
    ISSN: 1420-9071
    Keywords: Cartilage canals ; erysipelas arthritis ; rheumatoid arthritis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In experimentally-induced erysipelas polyarthritis, preexisting cartilage canals in articular cartilage play a crucial role during the very onset of the disease. This observation might have some implications for the pathogenesis of other infectious arthritides in young animals or even rheumatoid arthritis in man.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-0533
    Keywords: Bovine virus diarrhoea virus ; Porencephaly ; Hydranencephaly ; Ovine fetuses ; Antigen distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The distribution of viral antigen, histological lesions and inflammatory responses were examined in brains from ovine fetuses following experimental transplacental infection with a cytopathogenic strain of bovine virus diarrhoea virus (BVDV). At 10 and 14 days post inoculation (p.i.) viral antigen-containing cells were found throughout the different zones of the developing telencephalon and cerebellum. Corresponding to the distribution of viral antigen, necrotic lesions both of already differentiated and of undifferentiated fetal brain cells occurred. The extent and severity of microscopic lesions correlated positively with the number of viral antigen-containing cells. The destructive lesions were accompanied by meningeal and parenchymal cellular infiltrations predominantly with phagocytosing macrophages. In fetuses examined at 21 days p.i. a massive necrosis of the cerebral hemispheres and severe infiltrations with macrophages and CD3-positive lymphocytes had developed. In fetuses studied between 32 and 80 days p.i. porencephaly, hydranencephaly and leukoencephalomalacic lesions were present. In brain tissue of these fetuses, with the exception of two cases, BVD viral antigen was no longer detected.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 19 (1971), S. 155-165 
    ISSN: 1432-0533
    Keywords: Mink ; Thiamine Deficiency ; Disturbance of Permeability ; Astrocyte Oedema ; Degeneration of Neurons ; Pseudoencephalitic Syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Tissue lesions of thiamine deficiency in mink (Mustela vison) are predominantly located in the brain. Macroscopic lesions are bilateral symmetrical hemorrhages in the brain stem. Microscopically, signs of disturbance of vascular permeability and proliferation of endothelial cells may be found. Other lesions include a spongy appearance of the neuropil, homogenisation of axons, focal demyelination and occasionally malacias. Ischemic degeneration of neurons may be present in nuclei of the brain stem. The histologic lesions in some areas are similar to those of the pseudoencephalitic syndrome which is characteristic for Wernicke's encephalopathy in man.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Rheumatology international 6 (1986), S. 239-243 
    ISSN: 1437-160X
    Keywords: Cartilage canals ; Infectious arthritis ; Rheumatoid arthritis ; Articular cartilage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Porcine articular cartilage from cases of experimentally induced Erysipelas polyarthritis, a comparative model of rheumatoid arthritis (RA) in man, was examined with different histological and immunohistochemical techniques. The preexisting canals in articular cartilage played a crucial role during the flooding and deposition of arthritogenic microorganisms deep into the cartilage matrix. Subsequently this vascularized tissue mediated the same inflammatory reactions in hyaline cartilage of young animals as seen in other connective tissues. However, these stereotypical responses to injury were modulated by the unique composition and structure of articular cartilage.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1573-0832
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Es werden intracerebrale, orale und intramuskuläre Infektionsversuche mitCryptococcus neoformans (Cr.n.) an Tauben (Columbia livia) und Hühnern beschrieben. Die nach intracerebraler Infektion an Tauben erhaltenen Ergebnisse stellen eine Bestätigung der Befunde von Littmann, Borok & Dalton (1965) dar. Tauben lassen sich auch intramuskulär erfolgreich infizieren. Die mit zwei stark bekapselten und einem nahezu unbekapseltenCr.n.-Stamm durchgeführten Versuche ergaben keine Hinweise für eine höhere Virulenz des stark bekapselten Stammes. Unter Berücksichtigung der bei Tauben nachgewiesenen Spontaninfektionen (Weiland, Böhm & Abdallah, 1968) wird die Verbreitung vonCr.n. durch spontan infizierte Tauben als epidemiologisch bedeutsam angesehen. Es wird vermutet, daß resistenzmindernde Faktoren die Voraussetzung für das Angehen einerCr.n.-Infektion bei der Taube darstellen. Hühner erwiesen sich als besonders resistent gegenüber einerCr.n.-Infektion. Dennoch war es auch bei dieser Tierart möglich, eine letal ablaufende Infektion zu erzeugen. Über 100 kulturell untersuchte Hühnerkotproben sowie über 100 lebend gefangene Sperlinge (Passer domesticus) erwiesen sich als frei vonCr.n.
    Notes: Abstract Pigeons (Columba livia) and chicken were experimentally infected with well capsulated or with nearly uncapsulatedCryptococcus neoformans (Cr.n.) strains. In pigeons the intramuscular and intracerebral route was successful. Pigeons were said to be resistent against intramuscular infection. This could be refuted. Excretion ofCr.n. could be shown in one animal. Death or paralysis occurred only in a few animals, all other did not show distinct symptoms of illness. The animals were sacrified between 2 and 11 weeks after infection. After the second week none of the killed animals harbouredCr.n. in other localisations than brain. Brain infection could be demonstrated in some pigeons during the whole duration of the experiment. One of the animals was successfully infected with only 36 cells. Since spontaneous infections withCr.n. occur in pigeons (Weiland, Böhm & Abdallah, 1968) and the soil seems not to be the natural reservoir ofCr.n. (Böhm und Mitarb., 1970) we believe that natural infections of pigeons and the excretion with the faeces is an important factor in the epidemiology ofCr.n. Diseases which reduce the resistance of the pigeons (samonellosis, capillaria infection etc.) may be a supposition for aCr.n.-infection under natural conditions. One of 12 intracerebrally infected chickens (7 days old) succumbed after 4 days to a generalized cryptococcosis. None of 104 samples of old chicken faeces yieldedCr.n. Cr.n. could not be isolated from one of 103 sparrows (Passer domesticus), trapped in a city with heavy contaminated (Cr.n.) pigeon droppings.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1434-9949
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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