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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of pineal research 27 (1999), S. 0 
    ISSN: 1600-079X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Increasing evidence of the neuroimmunomodulatory role of the pineal gland prompted the present study of pineal gland expression of the immunoregulatory cytokine, interleukin (IL)-1β. IL-1β was constitutively expressed in the adult gland, with mRNA levels higher in glands collected during the photophase than in those collected during the scotophase of the light:dark cycle. IL-1β was up-regulated in pineal cultures, after treatment with either norepinephrine (NE) or interferon (IFN)/lipopolysaccharide (LPS). Although both astrocytes and microglia expressed IL-1β, important differences were found in the cellular expression of this cytokine under in vivo and in vitro conditions. Increased IL-1β expression by NE ex vivo and the decline in IL-I expression at night, when NE levels are elevated, can be explained by immunocytochemical data showing that astrocytes are the predominant cell type expressing this cytokine in vivo, whereas IL-1β-positive cells are predominantly microglia in pineal explants and dispersed cell cultures. These results are consistent with the hypothesis that cytokines secreted by pineal glia (astrocytes and microglia) may have an important regulatory role in the pineal gland.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Free Radical Biology and Medicine 9 (1990), S. 164 
    ISSN: 0891-5849
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Fermentation Technology 66 (1988), S. 193-198 
    ISSN: 0385-6380
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Nutritional Biochemistry 5 (1994), S. 78-83 
    ISSN: 0955-2863
    Keywords: 1,2-dimethylhydrazine ; carcinogenesis ; diet ; lipid peroxidation ; polyunsaturated fatty acids
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 28 (1985), S. 219-223 
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Relevant low energy data are analyzed in the framework of a generalSU(2) L ×SU(2) R ×U(1) B−L electroweak gauge model. The model is general in that it allows for a left-right asymmetric gauge coupling and introduces a most general mass term for the weak gauge bosons. It is shown that the recent μ-decay measurement, combined with neutral-current data, leads to the boundM w 2〉~180 GeV on the mass of the second charged weak boson. It is also noted that the recentB-meson life-time measurement, combined with constraints from theK L 0 −K S 0 mass difference, gives a weaker bound, i.e.M w 2≳140 GeV, independently of the structure of the leptonic sector.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 57 (2000), S. 1388-1398 
    ISSN: 1420-9071
    Keywords: Key words. Orphan nuclear receptors; COUP-TF; embryogenesis.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract. Chicken ovalbumin upstream promoter transcription factors (COUP-TFs) are orphan members of the steroid/thyroid hormone receptor superfamily. They have been shown to negatively regulate the activation function of vitamin D, thyroid hormone, retinoic acid, the retinoid X and the peroxisome proliferator-activated receptors. COUP-TF genes have been cloned from many species and their sequences are exceptionally conserved through evolution. This suggests a critical role for the COUP-TFs in these organisms. Indeed, the Drosophila COUP-TF, seven-up and mouse COUP-TFII are essential for development and differentiation during embryogenesis. Our current understanding of COUP-TF function suggests that they serve vital physiological roles during development despite extensive overlaps of expression. This defines the COUP-TFs as important factors in regulation of development and differentiation in multiple organisms.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 39 (1988), S. 475-477 
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Multiplicities of hadrons produced in μp scattering are analyzed with a diquark scattering model. it is assumed that a proton is composed of a quark and a scaler diquark and that both the quark and the diquark act as partons. A reasonable agreement between the experimental data and the predictions of the model is obtained. In particular, the observed large ratio of the proton to the overall positive hadron yield forx〉0.2 is successfully reproduced.
    Type of Medium: Electronic Resource
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