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  • 1
    Electronic Resource
    Electronic Resource
    Specific suppressor cells in graft–host tolerance of HLA-identical marrow transplantation (1981)
    [s.l.] : Nature Publishing Group
    Nature 292 (1981), S. 355-357 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Most long-term patients after human marrow transplantation from HLA-identical siblings are healthy stable chimaeras who need no further immunosuppressive therapy1'2. However, 30% of the chimaeras have mild to severe chronic GvHD characterized by lesions resembling those seen in autoimmune collagen ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/292355a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Canine osteosarcoma: Results of amputation with and without adjuvant immunotherapy (1978)
    Springer
    Cancer immunology immunotherapy 5 (1978), S. 181-186 
    Details
    ISSN: 1432-0851
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forty-eight dogs with spontaneously occurring osteogenic sarcoma (OS) were treated by amputation. Six dogs died soon after surgery, 34 dogs died or were euthanized 1–11 (median 4) months after, and eight dogs (17%) are alive 11–47 (median 21) months after amputation. Thirty-one dogs did not receive any therapy after amputation. Seventeen dogs received postamputation adjuvant immunotherapy consisting of intradermal bacillus Calmette-Guerin and an autologous tumor homogenate preparation administered every other week for 12 weeks. Twelve of these dogs were included in a prospectively randomized therapeutic trial in which a control group of 11 dogs received no therapy after amputation. Neither disease-free interval nor survival was prolonged by the immunotherapy protocol. Nevertheless, the current study demonstrates the feasibility of studying naturally occurring canine OS as a clinical and therapeutic model for OS in man.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00199626
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    Paper (German National Licenses)
    Fulltext
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