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  • 1
    Electronic Resource
    Electronic Resource
    Angiography in brain stem tumors (1974)
    Springer
    Neuroradiology 8 (1974), S. 99-112 
    Details
    ISSN: 1432-1920
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les données angiographiques de 17 tumeurs du tronc cérébral sont décrites en détail. L'importance des signes angiographiques précédemment décrits est confirmée. En général le prophil apparait plus riche d'informations que la projection de face. Les veisseaux sont parfois déformés seulement au niveau supérieur ou bien inférieur du tronc cérébral; ceci permet de reconnaître des tumeurs de petite taille et de les situer exactement. L'importance des mesures rélatives aux repères artériels et veineux décrites dans la litérature, est verifiée. On discute l'aspect des tableux atypiques et inhabituels —qui peuvent simuler des tumeurs de l'angle ponto-cérébelleux ou des méningiomes du grand trou occipital — et un cas faux-positif.
    Abstract: Zusammenfassung Der angiographische Befund von 17 Hirnstammtumoren wird ausführlich geschildert. Die Wichtigkeit von schon bekannten angiographischen Merkmalen wird bestätigt. Meistens ist die laterale im Vergleich zur Towneschen Aufnahme an diagnostischen Zeichen reicher. Die Dislokation der Gefäße ist manchmal auf diejenigen des oberen und des unteren Teils des Hirnstammes beschränkt. Dadurch wird die Darlegung und die genaue Lokalisation kleiner Tumoren im Hirnstamm ermöglicht. Des weiteren werden Kennzeichen von ungewöhnlichen und atypischen Fällen wie z.B. solche, die Kleinhirnbrückenwinkel-Tumoren und Foramen magnum Meningiome simulieren besprochen — und von einem falschpositiven Fall berichtet.
    Notes: Summary The angiographic findings of 17 brain stem tumors are reported in detail. The importance of the angiographic landmarks previously described is confirmed. Generally, the lateral view is found more informative than the Towne projection. The displacement of vessels is sometimes limited to those related to the upper or to the lower brain stem. This permits the recognition of small tumors and their position in the brain stem. The importance of the measurements of arterial and venous landmarks, described in the literature, is verified. The features of unusual paradoxical cases, simulating cerebellopontine angle lesions and posterior foramen magnum meningiomas, and of a false positive case, are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00345042
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  • 2
    Electronic Resource
    Electronic Resource
    Flow-cytometric analysis of DNA distribution after VP16-213 treatment of Lewis lung carcinoma (1983)
    Springer
    Cancer chemotherapy and pharmacology 10 (1983), S. 208-211 
    Details
    ISSN: 1432-0843
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The two dosage schedules of VP16 that gave the least and the greatest efficacy in Lewis lung carcinoma of the mouse were selected for evaluation of the cytokinetic effects observable in vivo at different intervals after treatment (schedule A: 40 mg/kg IV, on day 8 after transplant; schedule B: 13 mg/kg IV, repeated on days 8, 11 and 14 after transplant). After the single dose and after each repeated dose there was a marked increase in the percentage of cells in the LS-G2-M phases, with a corresponding decrease in the percentage of cells in G0-G1. The number of neoplastic tetraploid cells compared with normal diploid cells in the tumor was reduced after the single IV dose, and more markedly so after repeated doses. This study suggests that the more marked delay of cancer cell growth and greater effectiveness observed with schedule B is related to repeated blockade of the LS-G2-M phases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00255765
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  • 3
    Electronic Resource
    Electronic Resource
    Amelanotic leptomeningeal melanoblastosis. Case report (1990)
    Springer
    Neurological sciences 11 (1990), S. 171-175 
    Details
    ISSN: 1590-3478
    Keywords: Leptomeningeal melanoblastosis ; S-100 protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario La melanoblastosi leptomeningea è una rara facomatosi la cui variante amelanotica non è ancora stata descritta. Nel nostro studio consideriamo il caso di un ragazzo affetto da melanoblastosi leptomeningea amelanotica esordita come sindrome midollare e come sindrome ipertensiva endocranica secondaria. La diagnosi di melanoblastosi leptomeningea, suggerita dai dati liquorali e neuroradiologici, fu supportata dallo studio istopatologico.
    Notes: Abstract Leptomeningeal melanoblastosis is a rare phakomatosis; the amelanotic variant has not till now been described. In this paper we report the case of a young man suffering from amelanotic leptomeningeal melanoblastosis manifested as medullary syndrome and secondary intracranial hypertension. The diagnosis of leptomeningeal melanoblastosis was hypothesized on the basis of CSF and neuroradiological findings and it was finally confirmed by the histopathology.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02335561
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  • 4
    Electronic Resource
    Electronic Resource
    Clinical features and MR imaging in children with repaired myelomeningocele (1993)
    Springer
    Neurological sciences 14 (1993), S. 553-559 
    Details
    ISSN: 1590-3478
    Keywords: Myelomeningocele ; spinal cord malformation ; MR imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Scopo di questo studio è di contribuire alla definizione del ruolo delle malformazioni associate nell'evoluzione clinica del bambino affetto da mielomeningocele (MMC), sia essa stazionaria che peggiorativa. Sono stati studiati con Risonanza Magnetica 25 soggetti con MMC in età compresa tra i 7 anni e 3 mesi e i 18 anni e 10 mesi, seguiti con un lungo follow up clinico (almeno 7 anni). Sono state analizzate le relazioni tra le malformazioni associate, riscontrate all'esame di RM, e l'andamento clinico. I dati emersi sono i seguenti: 1) la presenza in tutti i soggetti di tethered cord fino ad ora rimasto asintomatico; 2) un'alta prevalenza (92%) di malformazione di Arnold Chiari; 3) una percentuale di siringomielia del 20%, corrispondente ai dati di letteratura con sintomatologia clinica presente in un solo caso; 4) la presenza di dilatazione ventricolare nel 72% dei casi, in assenza di sintomi di ipertensione endocranica. Si sottolinea l'importanza dell'individuazione precoce e di un follow up con RM degli aspetti malformativi per una più corretta condotta terapeutica.
    Notes: Abstract The aim of the study is to define the role of associated malformations in the clinical evolution of children affected by myelomeningocele. MRI investigation of the spinal cord was carried out on 25 patients between the age of 7.3 and 18.10 with MMC repaired and followed up for at least 7 years. The relation between associated malformations demonstrated by MRI and clinical trend was analysed. The results are the following: 1) presence of asymptomatic tethered cord in all cases; 2) high frequency (92%) of Chiari malformation; 3) presence of syringomyelia in 20% of patients, symptomatic in 1; 4) presence of ventricular enlargement in 72% of cases without increased intracranial pressure syndrome. For a better therapeutic approach prospective MRI studies are needed in order to follow up associated malformations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02339214
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  • 5
    Electronic Resource
    Electronic Resource
    Radiology of tumors spreading from middle fossa to posterior fossa or viceversa (1982)
    Springer
    Neurological sciences 3 (1982), S. 31-41 
    Details
    ISSN: 1590-3478
    Keywords: Meningioma ; pituitary adenoma ; epidermoid ; chordoma ; intracranial neurinomas ; chondroma ; glioma ; extra-axial tumors ; computed tomography ; angiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Sono stati riesaminati e descritti gli esami neuroradiologici di 31 casi consecutivi di tumori intracranici a cavallo tra fossa media e fossa posteriore, verificati chirurgicamente, con particolare riferimento all'esame radiografico del cranio, all'angiografia ed alla tomografia assiale computerizzata. Nella maggior parte dei casi l'analisi comparata dei diversi esami è stata determinante per giungere ad una diagnosi di natura della lesione.
    Notes: Abstract 31 consecutive, surgically verified cases of tumors growing from the middle into the posterior fossa or viceversa are reviewed. The results of plain X-ray studies, of angiography and computed tomography (CT)are described. Comparative analysis of the various studies was decisive for predicting the nature of the lesion in the majority of the cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02043345
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  • 6
    Electronic Resource
    Electronic Resource
    Intra-arterial digital subtraction angiography of vascular lesions of the spinal cord. Personal experience (1986)
    Springer
    Neurological sciences 7 (1986), S. 515-519 
    Details
    ISSN: 1590-3478
    Keywords: Arteriovenous malformation ; spinal cord ; digital subtraction angiography ; embolization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario Gli AA riferiscono la loro esperienza sull'impiego dell'angiografia digitalizzata per via arteriosa nello studio e nell'embolizzazione delle malformazioni arterio venose del midollo spinale (16 esami a scopo diagnostico e 2 embolizzazioni su 6 pazienti). Questa tecnica si è dimostrata la più indicata per questo tipo di esame e per gli interventi di embolizzazione ad esso connessi.
    Notes: Abstract IDSA studies were performed in 6 patients with AVM and hemangioblastomas of the spinal cord. IDSA appears to be the most suitable angiographic approach for the study and embolization of this kind of lesions of the spinal cord even when special conditions require repeating some injections on conventional angiography.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02342030
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  • 7
    Electronic Resource
    Electronic Resource
    Intracranial tumors arising from the floor of the middle fossa (1985)
    Springer
    Neurological sciences 6 (1985), S. 469-475 
    Details
    ISSN: 1590-3478
    Keywords: Floor of the middle fossa ; meningiomas ; metastases ; trigeminal neurinomas ; epidermoids ; chordomas ; chondromas
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario È stata fatta una revisione di tumori del pavimento della fossa media, operati all'Istituto Neurologico “C. Besta” di Milano e verificati istologicamente. I tumor primitivi più frequenti sono i meningiomi e i neurinomi del Vo nervo cranico. Le lesioni maligne sono piuttosto rare; tra queste più comuni le metastasi. Tra i tumori benigni vi sono gli epidermoidi, i cordomi e i condromi. Questi tumori sono stati esaminati e confrontati fra loro dal punto di vista angiografico, tomodensitometrico e radiografico convenzionale con particolare attenzione a problemi di diagnosi differenziale.
    Notes: Abstract Tumors involving or arising from the floor of the middle fossa in cases seen at the Neurological Institute C. Besta were reviewed, and the radiological findings of plain films, angiographic and CT studies are described. Meningiomas, metastases, trigeminal neurinomas, epidermoids, chordomas and chondromas were included in the study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02331040
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