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  • 1
    ISSN: 1437-2320
    Keywords: Clinical trial ; contrast enhancement ; gadolinium-DTPA ; MRI contrast agents
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This report concerns a clinical trial with Gd-DTPA as an intravenous contrast medium for MRI in patients with neurological disorders. 50 patients (30 female, 20 male) were examined without and with Gd-DTPA and the results of CT scanning and MR scanning without and with Gd-DTPA were compared. All patients tolerated the contrast medium very well. In the various patient groups, Gd-DTPA often added to the information. This was especially true in the tumor group, where better delineation of tumor, blood, and edema was obtained.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Neurosurgical review 9 (1986), S. 43-47 
    ISSN: 1437-2320
    Keywords: NMRI ; NMR spectroscopy ; sensitivity ; specificity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A brief survey is given of the state of art of NMRI in neurosurgical diagnosis and its advantages and disadvantages in comparison to CT scanning are discussed. Specificity and sensitivity of these methods are also considered.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-2161
    Keywords: Medulloblastoma ; Extraneural spread ; Bone metastases ; MR imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The findings of MR imaging in 3 patients with bone metastases from medulloblastoma are reported. The first patient showed focal lesions of low signal intensity on T1-weighted spin echo images at a time when bone scintigraphy was negative for metastases. This patient later developed extensive osteosclerotic lesions visible on plain films. The bone marrow of the second patient showed diffuse low signal intensity on T1-weighted images. After chemotherapy the signal intensity of the bone marrow increased which correlated with a return of normal hematopoietic tissue. A response to chemotherapy was also found on MR imaging and repeat bone marrow biopsies in a third patient. A consistent finding was a low signal intensity on pre-gadolinium images, but the pattern (focal or diffuse abnormal signal intensity) was different in each patient. To our knowledge, this is the first report on MR imaging findings in bone metastases from medulloblastoma.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    The international journal of cardiovascular imaging 9 (1993), S. 59-69 
    ISSN: 1573-0743
    Keywords: CABG ; magnetic resonance ; PTCA ; revascularization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Magnetic resonance imaging (MRI) is a non-invasive modality which can be used for direct visualization of coronary artery bypass grafts. Spin-echo and gradient-echo (cine-MRI) techniques are now available on standard MR machines and provide information on graft morphology and graft patency with a 90% accuracy. By combining the standard techniques with MR phase velocity mapping, the flow rate in the graft can be measured, thereby offering a unique non-invasive assessment of the graft function. Newer techniques include MR coronary angiography, pharmacologically induced stress MRI, ultrafast MRI of the first-pass (perfusion) of a paramagnetic contrast agent through the myocardium, and31P MR spectroscopy of high-energy phosphate metabolism of the myocardium. All of these may develop into valuable diagnostic tools for the assessment of functional results after CABG or PTCA, but still require clinical validation. At present, MRI is a useful screening procedure for assessment of graft patency and function in post-operative pain syndromes and in late graft occlusion or stenosis.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1433-0350
    Keywords: Spina bifida ; Spinal cord malformations ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The incidence of associated malformations of the hindbrain and spinal cord in patients with spina bifida was investigated by a clinical and magnetic resonance study. The incidence of these malformations in combination with spina bifida was 49/53 (92.5%). Fiftytree children born with spina bifida aperta (40 patients) or spina bifida occulta (13 patients) formed the study group. The incidence of the various malformations were: Chiari malformations, type I, 10/53 (19%), and type II, 20/53 (38%); syringomyelia, 13/53 (24.5%); hydromyelia 4/53 (7.5%); tethered cord malformation, 35/53 (66%); diastematomyelia 2/53 (4%). Thirty-seven of the 49 patients with associated malformations had no clinical signs at the time of our study. The results point to the fact that in the pediatric age group, associated spinal defects often remain asymptomatic.
    Type of Medium: Electronic Resource
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