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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Munksgaard International Publishers
    Community dentistry and oral epidemiology 31 (2003), S. 0 
    ISSN: 1600-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract – Objectives: The aim of the study was to investigate the caries-preventive effect of high-filled glass ionomer sealant in newly erupted first molars in a high-risk group. This investigation is part of a larger study amongst eight hundred and thirty-five 6–7-year-old Syrian children.Methods: Children that had 1, 2 or 3 just erupted or erupting and at least one unerupted first molar (control) were enrolled in this pilot study. A total of 60 children fulfilled the inclusion criteria. There were 49 children with a total of 83 sealants available for examination at the evaluation year 5.Results: Almost two out of the three sealants (69%) had disappeared between evaluation years 2 and 3. 1.2% (SE = 1.2) of the sealants survived were fully retained and 10.3% (SE = 3.3) of the sealants survived were fully and partially retained at the evaluation year 5. Caries prevalence of the children in the study group at the evaluation year 5 was 55%. The Odds ratio concerning sealed and control group at year 5 was 2.6 with 95% confidence limits of 1.2 and 5.7, implying a relative risk (RR) of 2.1. Unsealed unerupted first molars had 2.1 times higher chance than sealed newly erupted first molars to develop dentinal lesions in this child population after 5 years.Conclusions: It is concluded that sealing newly erupted first molars with high-filled glass ionomer may be a caries-preventive measure in high-risk children. However, a well-designed clinical trial should be implemented to confirm the initial findings.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives:  Bone remodelling during orthodontic tooth movement is related to the expression of mediators in gingival crevicular fluid (GCF). No information is available concerning the effect of age on the levels of these mediators in GCF. The purpose of this study was to quantify three mediators (prostaglandin E2, interleukin-6 and granulocyte-Macrophage Colony-Stimulating Factor) in GCF during orthodontic tooth movement in juveniles and adults.Material and methods:  A total of 43 juvenile patients (mean age 11 ± 0.7 year), and 41 adult patients (mean age 24 ± 1.6 year) took part in the study. One of the lateral incisors of each patient was tipped labially, the other served as control. GCF samples were taken before force activation (t0) and 24 h later (t24). Mediator levels were determined by radioimmunoassay (RIA).Results: PGE2 concentrations were significantly elevated at t24 in juveniles and adults, while concentrations of IL-6 and GM-CSF were significantly elevated only in juveniles. Total amounts of all three mediators in GCF significantly increased at t24 in both groups.Conclusions:  In early tooth movement, mediator levels in juveniles are more responsive than levels in adults, which agrees with the finding that the initial tooth movement in juveniles is faster than in adults and starts without delay.
    Type of Medium: Electronic Resource
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