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  • 1
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 9 (1988), S. 683-698 
    ISSN: 0192-253X
    Keywords: variegation ; bristles ; pigmentation ; patterns ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: In D. hydei two new mutants, In(1)f3 and IN(5)Z, show obvious mosaic gene expression. Their phenotypic expression is susceptible to the breeding temperature and to the addition of a supernumerary Y chromosome to the chromosome set. In this respect the mutants resemble standard cases of position-effect variegation based on the action of heterochromatin. However, since neither centromeric nor sex chromosomal heterochromatin apparently are involved, the mutations point to a new type of variegation provoked by euchromatic sections. The mosaic patterns of these mutants, in particular those of In(1)f3, will be described.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 8 (1987), S. 45-58 
    ISSN: 0192-253X
    Keywords: white-mottled ; Malpighian tubules ; gene action ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Riboflavin deposition in organs of Drosophila hydei was studied by means of a growth test using a riboflavin-deficient strain of the fungus Aspergillus nidulans. In wild-type animals, riboflavin is deposited in Malpighian tubules (MT) and testes but not in adult eyes. Certain white (w) mutants do not contain riboflavin, whereas intermediately colored w mutants contain minor amounts of the substance. Riboflavin-containing MT cells contain special globules that can be fixed and stained with the redox dye phenazine-methosulphate. The number and size of these granules is related to growth effect and point to a role of the w locus in the intracellular deposition of riboflavin in special organs. In white-mottled (wm) position-effect variegation mutants, a significant correlation was found between the extent of variegation (percentage of yellow cells) and riboflavin content (growth effect) of the MT. However, the individual variation of cell phenotype was extremely large and exaggerated types were observed indicating “overdominance” of the rearranged w+ gene. This contradicts an unsubstantiated dogma of position-effect variegation that assumes that the affected gene simply switches between the on and off state, as is discussed.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Developmental Genetics 6 (1985), S. 257-268 
    ISSN: 0192-253X
    Keywords: Drosophila hydei ; cell death ; imaginal discs ; wing reduction ; Life and Medical Sciences ; Genetics
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology
    Notes: Cell death and its effect on wing size have been described in some wing mutants of Drosophila hydei. Dead cells in the imaginal discs were localized by Nile-bule and acridine-orange staining. Various Notch (N) alleles, the mutation Costal-nick (Cnk) and the compound N/Cnk show characteristic patterns of cell death in the imaginal wing disc. Some but not all of the structural features of the adult wing can be related to the site of cell death during larval stages. In NAx types, extensive cell death is followed by regenerative growth, invalidating a simple relation between size of the disk and size of the wing. In Nts/Cnk cell death and wing morphology depend on the breeding temperature. From temperature experiments we conclude that cell death starts between day 4 and 5 after egg laying and can be induced by a shift to the restrictive temperature during the critical phase. Patterns of wing incisions and cell death in Nts/Cnk genotypes seem not to be delimited by any of the known compartment boundaries.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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