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  • 1
    ISSN: 1432-2161
    Schlagwort(e): Key words Classification ; Fractures ; MRI ; Thoracolumbar spine
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  Objective. To define the state of different structures of the fractured thoracolumbar spine which may play a role in the immediate and long-term mechanical stability on MR images and to investigate the relationship of these findings with the AO classification of spinal injuries. Design. The state of the anterior longitudinal ligament, posterior longitudinal ligament, posterior ligamentous complex, cranial and caudal endplates, cranial and caudal discs and the vertebral body were defined using clinical, experimental and radiological data. The state of these structures was reported for each fracture on the MRI examinations and the different MRI features appropriate for different fracture classes were defined. Patients. MRI examinations of 70 patients with 100 fractures of the thoracolumbar spine were used for this study. Results. Wide variations were seen in the state of the structures studied. We could not find a definite pattern to relate these findings with the AO classification scheme. Conclusions. MR findings should be integrated into future classification schemes of thoracolumbar spine fractures. This would enable specific data about the structures involved in the stability of the spine to be acquired. Prospective studies using the criteria developed in this study may help resolve some of the controversies concerning the diagnosis and prognosis of these injuries as well as the development of new classification systems.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Anatomy and embryology 133 (1971), S. 172-183 
    ISSN: 1432-0568
    Schlagwort(e): Notochord ; Methods ; Artefact
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Das Phänomen der segmentalen Wellen der Chorda dorsalis wurde bei Mäuse-, Ziegen- und Schafs-Embryonen sowie auch bei menschlichen Embryonen untersucht. Die möglichen postmortalen Momente für das Entstehen der Wellen konnten ausgeschlossen werden: Die Wellen sind nicht zurückzuführen auf eine Bearbeitung des Präparates. Wir müssen die Wellenform als intravitales Phänomen betrachten, das wahrscheinlich durch Prozesse in der frühembryonalen Entwicklung verursacht wird.
    Notizen: Summary The phenomenon of the segmental flexures of the notochord has been studied in embryo's of mice, sheep, goats, and men. A number of postmortal events as a cause for the flexures of the notochord, could be excluded: the flexures are not a result of the histological technique. We consider therefore the segmental flexures as an intravital phenomenon probably caused by processes during the embryonic development.
    Materialart: Digitale Medien
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    European journal of orthopaedic surgery & traumatology 7 (1997), S. 181-185 
    ISSN: 1432-1068
    Schlagwort(e): Osteomyelitis ; Pediatrics ; Therapy ; Ostéomyélite ; Orthopédie pédiatrique ; Traitement
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Résumé L'ostéomyélite hématogéne de l'enfant est une maladie grave. Bien que tous les segments osseux puissent être atteints, les localisations préférentielles sont l'extrémité distale du fémur et l'extrémité proximale du tibia. L'ostéomyélite aiguë peut être suspectée par l'interrogatoire et l'examen clinique. Les signes sont souvent moins évocateurs dans l'ostéomyélite chronique. La radiographie peut parfois montrer un épaississement des parties molles dans les premiers jours, puis une destruction osseuse avec appositions périostées. Le passage à la chronicité est le fait des retards thérapeuttiques. Il n'y a pas de consensus dans la littérature sur le traitement optimal de l'ostéomyélite. Dans tous les cas nous avons réalisé un geste chirurgical : fenêtre osseuse, drainage de l'abcès, excision des tissus nécrotiques. Les prélèvements bactériologiques étaient systématiques, guidant le traitement antibiotique par voie intraveineuse puis orale. Le but de ce travail rétrospectif était d'évaluer les résultats de ce traitemnt de l'ostéomyélite chez l'enfant, et particulièrement le taux de guérison et de récidive. De 1987 à 1994, 28 enfants ont été admis dans notre service pour ostéomyélite hématogène. Ont été étudiés sur dossiers l'anamnèse, le tableau clinique, la démarche diagnostique, le traitement et son résultat. Le tableau était aigu dans 12 cas et chronique dans 16 cas. L'âge moyen était de 5,5 ans (de 1,2 à 16,3 ans) dans les cas aigus et de 5,9 ans (de 0,8 à 13,6 ans) dans les cas chroniques. La température à l'admission était respectivement de 38,4 et de 37,3°C. Les valeurs moyennes de la vitesse de sédimentation , de la proténe C-réactive et de la leucocytose étaient respectivement de 49 mm/h, 111 mg/l et 16,2 x 109/l. Des anomalies radiologiques étaient visibles dans 6 cas aigus et 16 cas chroniques. Les cultures étaient positives dans 9 cas aigus et 7 cas chroniques, et du Staphylocoque Aureus a été retrouvé 8 fois. Dans les cas aigus, la durée moyenne du traitement antibiotique était de 20 jours (de 14 à 30 jours) par voie intraveineuse et de 22 jours (de 21 à 28 jours) par voie orale. Dans les cas chroniques, les chiffres respectifs étaient de 20 jours (de 8 à 32 jours) et 25 jours (de 21 à 45 jours). La durée moyenne d'hospitalisation était de 23 jours dans les deux groupes. Le suivi moyen était de 3,7 ans (de 0,7 à 8,3 ans) pour les cas aigus et de 2,7 ans (de 0,4 à 7,6 ans) pour les cas chroniques. A la fin du traitement, tous les patients, à l'exception d'un seul, étaient considérés comme guéris, et les paramères de surveillance étaient normaux. Trois patients avaient des séquelles fonctionnelles. Il apparaît qu'un traitement chirurgical associé à une antiobiothérapie de 6 semaines est suffisant pour guérir les ostéomyélites hématogènes aiguës ou chroniques de l'enfant.
    Notizen: Summary From 1987 to 1994, 28 children were admitted to our hospital with a haematogenous osteomyelitis. They were evaluated by chart review for history, clinical presentation, diagnostic work-up, treatment and outcome. The patients were considered to have an acute (n=12) or a chronic osteomyelitis (n=16). The mean age was 5.5 years and 5.9 years, respectively. Clinical symptoms such as local tenderness and swelling were present for 8 and 128 days, respectively. The mean temperature at admission was 38.4 and 37.3°C, respectively. The ESR, CRP and WBC were elevated in children with an acute osteomyelitis. In chronic osteomyelitis cases these findings were less elevated. On the X-rays in 6 and 16 children, respectively, abnormalities were visible. All children underwent a surgical procedure: a cortical window was made, pus was drained and necrotic tissue was excised. Positive cultures were obtained in 9 and 7 children, respectively. Subsequently, all patients were treated with i.v. and oral antibiotics. The mean duration of i.v. plus oral antimicrobial therapy was 20 plus 22 days for acute osteomyelitis and 20 Plus 25 days for chronic osteomyelitis. The mean duration of hospitalisation was 23 days in both groups. The mean follow-up was 3.7 years for patients with an acute osteomyelitis and 2.7 years for patients with a chronic osteomyelitis. After treatment, all but one patients were clinically well and the infection parameters had returned to normal values. Three patients had residual signs (ankylosis, decreased function). After surgical intervention it appears that six weeks of antibiotic therapy is sufficient to eradicate acute as well as chronic osteomyelitis in children.
    Materialart: Digitale Medien
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  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Surgical and radiologic anatomy 12 (1990), S. 43-51 
    ISSN: 1279-8517
    Schlagwort(e): Cryosections ; Magnetic resonance imaging ; Neonatal hip anatomy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Résumé L'anatomie complexe de la hanche du nouveau-né est souvent difficile à illustrer. Récemment, l'IRM a été utilisée pour étudier la hanche normale et pathologique du nouveau-né. Nous avons corrélé des explorations IRM de la hanche d'un enfant mort-né avec des cryosections faites dans divers plans. La technique de coloration de Mallory-Cason a été utilisée pour montrer le détail des structures anatomiques de la hanche normale. Dans ce travail l'IRM s'est avérée un excellent moyen d'exploration de l'anatomie de la hanche.
    Notizen: Summary The complex anatomy of the neonatal hip is often difficult to image. Recently, magnetic resonance imaging (MRI) has been used to evaluate the normal and abnormal neonatal hip. We correlated the MRI scans of the hip of a newborn cadaver with multiplanar cryo-sections stained according to Mallory-Cason, to detail the anatomic structures of the normal hip joint space. In our experience, MRI was shown to provide excellent depiction of hip anatomy.
    Materialart: Digitale Medien
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  • 5
    Digitale Medien
    Digitale Medien
    Springer
    Surgical and radiologic anatomy 12 (1990), S. 15-16 
    ISSN: 1279-8517
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 6
    Digitale Medien
    Digitale Medien
    Springer
    Acta biotheoretica 25 (1976), S. 219-258 
    ISSN: 1572-8358
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Summary The literature on the early embryonic development of the vertebral column in various animal species was analyzed to evaluate so many unrelated or contradictory observations. The recurring problems are described. One of the first was the lack of correspondence between the metameric boundaries of the ‘primitive vertebral bodies’ arising from the somites and those of the adult vertebral bodies, as presumably shown by their relationship to the vertebral processes and spinal nerves. A century ago, Remak introduced the concept of ‘Neugliederung’, according to which the ultimate vertebral body boundaries are determined by a shift of a half segment in comparison with the earlier segment boundaries.
    Materialart: Digitale Medien
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  • 7
    Digitale Medien
    Digitale Medien
    Springer
    Journal of materials science 8 (1997), S. 799-802 
    ISSN: 1573-4838
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin , Technik allgemein
    Notizen: Abstract Tobramycin release from tobramycin-containing bone cement was studied in vivo in a rabbit model. After insertion of cement into the right femur, tobramycin concentration as a function of time for up to 28 days was measured in serum and bone of rabbits. Tobramycin release in the femoral cortex adjacent to the cement was found to exceed the minimal inhibitory concentration for Staphylococcus aureus Wood 46. Serum tobramycin concentrations were below the systemic toxicity threshold.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 8
    ISSN: 1573-4838
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin , Technik allgemein
    Notizen: In the present study the potential of Polyactive® bilayer sheets in the prevention of scar tissue formation after spinal surgery was investigated. Eight adult beagle dogs underwent 3 laminectomies at three levels (L2, L4 and L6). According to a randomized implantation schedule a Polyactive® sheet or autogenous fat graft was placed in the defect. The third site served as a control without implant. After 4 or 12 weeks (4 dogs per period) the dogs were sacrificed and histological sections were prepared. The Polyactive® treated defects showed partial closure by newly formed bone. The Polyactive® was encapsuled by a thin fibrous tissue layer. Ventral to the defect, dense fibrous tissue was present which was separated from the dura by the Polyactive® sheet in all cases. In some cases fibrous tissue was present between the implant capsule and the dura. In the fat graft group there were no signs of closure of the defect but most sites showed fibrous tissue at the edges of the graft, which was in 4 sites continous with the dura mater. Fibrosis and degeneration of the fat grafts were seen. All control defects showed partial closure by newly formed bone, and ventral to the defect extensive fibrous tissue, which was in 50% continous with the dura mater. Other sections showed loose connective tissue in contact with the dura mater. It is concluded that Polyactive® has a potential as a mechanical barrier in the prevention of adhesions between the dorsal spinal muscles and the dura mater.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 9
    Digitale Medien
    Digitale Medien
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 41 (1998), S. 574-583 
    ISSN: 0021-9304
    Schlagwort(e): artificial implants ; calcium phosphates ; titanium ; osteointegration ; arthroplasty ; Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Medizin , Technik allgemein
    Notizen: The early healing phase of hard tissue implants is important to their long-term success. Problems during this phase can result in a so-called primary biological failure. In 24 New Zealand white rabbits, the healing in cortical bone of noncoated TiAlV and cpTi cylinders and of TiAlV cylinders plasma-spray-coated with hydroxyapatite (HA) or fluorapatite (FA) was investigated histologically and histomorphometrically after 3, 7, 14, and 28 days. Histomorphometry consisted of bone contact measurements and the use of a new semi quantitative scoring system that discriminated various tissues in contact with the implant. The results demonstrated that the most important parameter in initial implant healing is the bone itself and not the characteristic of the implanted material. For all implants, healing was characterized by a sequence of hematoma formation, bone resorption, and new bone formation where the initial press-fit situation revealed more bone-implant contact than after 7 and 14 days. There were only minor differences between the implant types: the new bone formation directly on the implant surface was qualitatively histologically superior to the CaP-coated implants, but this could be confirmed with the scoring method only for the HA-coated implants. It is concluded that initial press-fit fixation in cortical bone is not an end situation; rather, what happens is that as a result of interface remodeling, early postoperatively implant integration in the bone will decrease temporarily prior to a subsequent phase of new bone formation. © 1998 John Wiley & Sons, Inc. J. Biomed Mater Res, 41, 574-583, 1998.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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