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  • 1
    Electronic Resource
    Electronic Resource
    The effect of digitoxose on feeding behavior (1983)
    Springer
    Cellular and molecular life sciences 39 (1983), S. 979-984 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The effect of digitoxose (DIG) on food intake, gold thioglucose (GTG) lesion formation in the ventromedial hypothalamus (VMH), and VMH glucose oxidation in vitro was investigated in mice. DIG significantly decreased the amount of food ingested during the day compared to controls (p〈0.01). DIG had no effect on nocturnal feeding. GTG lesion formation in the VMH and VMH glucose oxidation were not altered by DIG treatment. These results suggest that DIG alters daytime feeding behavior by affecting extrahypothalamic or peripheral glucoreceptor sites.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01989763
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Glucose oxidation in the ventromedial hypothalamus is not affected by insulin or ouabain but depressed by alloxan treatment (1980)
    Springer
    Experimental brain research 40 (1980), S. 464-467 
    Details
    ISSN: 1432-1106
    Keywords: Ventromedial hypothalamus ; Alloxan ; Insulin ; Ouabain ; Glucose oxidation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Insulin is apparently not required for VMH glucose oxidation in vitro. Ouabain, an inhibitor of the Na-K pump ATPase, does not prevent VMH glucose oxidation in vitro. These data suggest (a) the VMH does not exhibit a cotransport phenomenon of glucose with the Na-K pump mechanism, and (b) glucose oxidation in the VMH is not insulin dependent. Alloxan-diabetes was induced to increase tissue insulin sensitivity. A comparison of glucose oxidation rates in alloxan-diabetic VMH tissue and normal VMH tissue, supplemented only with saline, indicated a highly significant (p 〈 0.001) depression of glucose oxidation in the alloxan-treated tissue. Cell membranes in the VMH are perhaps altered by alloxan.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00236155
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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