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  • 1
    Electronic Resource
    Electronic Resource
    Direct profilometry of the skin: its reproducibility and variability (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 5 (1995), S. 0 
    Details
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective The degree of reproducibility and precision of the mechanical direct profilometry and the intra- and interindividual fluctuations of 7 surface parameters were investigated.Material and methods Negative replicas were sampled from defined areas of the skin of 31 volunteers an evaluated with the profile-tracking device TKC 300 Hommeltester in order to derive data about the inter- and intraindividual fluctuations. To determine the precision of this method 6 roughness parameters and J of waviness of each replica were repetitively evaluated. The practicability was tested introducing minimal changes in the experimental set-up. Further, the effect of urea-containing creme on the skins topography was investigated in a double-blind clinical setting on a collective of 11 patients.Results The precision of this method is shown by nearly unchanged topographic parameters. Moreover, our data show smaller intra- than interindividual fluctuations of roughness (Ra) and waviness (Wt), being an important demand for clinical investigations.Conclusion In this paper we demonstrate that the parameters of both roughness as well as the recently introduced waviness can be conveniently evaluated with a high degree of precision with the direct profilometry.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-3083.1995.tb00428.x
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  • 2
    Electronic Resource
    Electronic Resource
    In vitro cytotoxicity of antimicrobial agents to human keratinocytes (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 6 (1996), S. 0 
    Details
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Backround The degree of bacterial contamination in the wound bed plays a key role in determining the level of “take” of keratinoeyte grafts in burn patients. This study was done to evaluate the best suited antimicrobial agent for topical application in relation to antimicrobial activity and cytotoxic effect on graft cells.Objective The cytotoxicity of 7 antibacterial agents (gentamicin sulphate, ciprofloxacin hydrochioride, bacitracin, polymyxin B sulphate, diethanolamin salt of fusidic acid, teicoplanin, vancomycin hydrochtoride), one anlifungal substance (amphotcricin B sodium deoxycholate) and one antiseptic agent (povidone iodine) on cultured human keratinocytes, HaCaT keratinocytes and fibroblasts was investigated.Material and methods The effects of these agents were tested using two separate assays - the neutral red assay and the Bradford protein assay. In order to assess toxicity of the agent, the obtained midpoint cytotoxicity (MC50) was compared to the respective minimal inhibitory concentration (MIC) for receiving the cytotoxic potential in microbiologically effective doses.Results Antibiotics effective against Staphylococcus aureus with a small potential of toxicity are Bacitracin, Fusidic acid, Vancomycin and Tcicoplanin. Gentamicin and Ciprofloxacin are effective against both Staphylococcus aureus and Pseudomonas aeruginosa with a low potential of toxicity.Conclusion The use of antimicrobial agents with a midpoint cytotoxicity (MC50) higher than the minimal inhibitory concentration (MIC) by at least a factor of 100 might reduce the risk of toxic injury to graft cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-3083.1996.tb00160.x
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  • 3
    Electronic Resource
    Electronic Resource
    Intra- and interindividual variations of direct profilometry of different skin areas (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 8 (1997), S. 0 
    Details
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-3083.1997.tb00460.x
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  • 4
    Electronic Resource
    Electronic Resource
    DIAGNOSIS AT FIRST GLANCE: THE BABOON SYNDROME (1996)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of dermatology 35 (1996), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-4362.1996.tb01667.x
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  • 5
    Electronic Resource
    Electronic Resource
    Über die Herzmittelwirkung am arsenvergifteten Froschherzstreifen (1930)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 156 (1930), S. 176-182 
    Details
    ISSN: 1432-1912
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01859321
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  • 6
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    The Egyptian War of 1882 (Book Review) (1885)
    London : Periodicals Archive Online (PAO)
    The RUSI journal. 28 (1885) 279 
    Details
    ISSN: 0307-1847
    Topics: Political Science
    Notes: REVIEWS
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:p225-1885-028-00-000016
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  • 7
    Electronic Resource
    Electronic Resource
    Multiple kutane Neoplasien bei Cyclosporin-Therapie nach Nierentransplantation (1995)
    Springer
    Der Hautarzt 46 (1995), S. 638-642 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Cyclosporin A ; Immunsuppression ; Kutane Neoplasien ; Key words Cyclosporin A ; Immunosuppression - Cutaneous neoplasms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary We report on a 56-year-old renal allograft recipient receiving cyclosporin A immunosuppression. During this therapy he subsequently developed the following cutaneous neoplasms: squamous cell carcinomas, basal cell carcinomas, Bowen's disease, actinic keratosis, sebaceous hyperplasia, a dysplastic naevus and, finally a nodular malignant melanoma. Adverse effects of the cyclosporin A therapy are discussed, with special reference to dermatologic effects and the implications for patient and doctor.
    Notes: Zusammenfassung Wir berichten über einen 56jährigen Patienten, der unter Cyclosporin-Behandlung aufgrund einer Nierentransplantation multiple kutane Neoplasien entwickelte. Zu diesen Tumoren, die operativ entfernt wurden, zählten spinozelluläre Karzinome, Basaliome, M. Bowen, aktinische Keratosen, Talgdrüsenhyperplasien, ein dysplastischer Nävus und zuletzt ein noduläres malignes Melanom. In Anlehnung an diese Kasuistik wird die Cyclosporin-Therapie in Hinsicht auf Konsequenzen für Arzt und Patient unter besonderer Berücksichtigung der dermatologischen Seite diskutiert.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050311
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  • 8
    Electronic Resource
    Electronic Resource
    Rückstände des Coccidiostatikums Amprolium in Fleisch und Eiern (1980)
    Springer
    European food research and technology 170 (1980), S. 329-333 
    Details
    ISSN: 1438-2385
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Description / Table of Contents: Zusammenfassung Für das Coccidiostatikum Amprolium wird ein einfaches und rasch durchführbares Verfahren zur Rückstandsanalyse beschrieben, bei dem der Wirkstoff zu 2-Picolin gespalten und dieses gaschromatographisch mit dem stickstoffselektiven thermionischen Detektor bestimmt wird. Zusatzversuchezeigen, daß sich Amprolium in Hühnerfleisch und Eiern bis hinunter zu 0,01 mg/kg quantitativ und sehr reproduzierbar wiederfinden läßt. Ergebnisse der Untersuchung von Eiern und Fleisch von Hühnern nacheiner Behandlung mit Amprolium sowie von Ei- und Fleischproben aus dem Handel werden mitgeteilt.
    Notes: Summary A simple and rapid gas chromatographic procedure for the residue analysis of the coccidiostat amprolium in muscle tissue, organs and eggs is described. The quaternary compound is cleaved by an excess of sulphite, yielding 2-methylpyridine which is detected by gas chromatography using the nitrogen-selective thermionic detector. Amprolium added to eggs and poultry meat at levels between 0,01 and 1,0 mg/kg was recovered quantitatively and with very high reproducibility. Results are given for residues found in eggs and meat of laying hens fed with amprolium and for commodities purchased locally.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01042968
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  • 9
    Electronic Resource
    Electronic Resource
    Eine neue deutsche Aleochara aus Maulwurfnestern (1954)
    Springer
    Naturwissenschaften 41 (1954), S. 238-239 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00635138
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  • 10
    Electronic Resource
    Electronic Resource
    Das Aufgebotsverfahren in Warenzeichensachen (1948)
    Weinheim : Wiley-Blackwell
    Zeitschrift für die chemische Industrie 20 (1948), S. 43-45 
    Details
    ISSN: 0044-8249
    Keywords: Chemistry ; General Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ange.19480200113
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