ISSN:
1573-0646
Keywords:
pyrazoloacridine
;
germ cell tumor
;
cisplatin-refractory
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Abstract Thirteen patients with cisplatin-refractory germ cell tumors weretreated on a Phase II trial with pyrazoloacridine.Pyrazoloacridine was given intravenously at 600 mg/m3 everythree weeks. The median nadir leucocyte count was 2.5cells/mm3, hemoglobin was 10.8 g/dl, and platelet count was126,000 cells/m3. None of the thirteen evaluable patientsachieved a major response. Pyrazoloacridine is not efficaciousin the treatment of cisplatin-refractory germ cell tumors.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1006434008357
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