ISSN:
1089-7623
Source:
AIP Digital Archive
Topics:
Physics
,
Electrical Engineering, Measurement and Control Technology
Notes:
By using a reference-beam diffraction data-collection technique, it is possible to directly measure a large number of relative phases of Bragg reflections on an area detector in a typical protein crystallography experiment. The technique, being developed at Cornell, incorporates the principle of three-beam diffraction into the most common method of data collection, i.e., the oscillating-crystal method, and allows recordings of many phase-sensitive three-beam interference profiles simultaneously. Recent advances include a dedicated five-circle κ diffractometer and new data acquisition and analysis algorithms. Experimental results on a protein crystal are presented and the strategies of using the measured phases for solving crystal structures are discussed. © 2002 American Institute of Physics.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1063/1.1445828
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