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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 90 (2001), S. 1920-1923 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Co-based Gd3Co29−xCrx compounds with a Nd3(Fe,Ti)29-type of structure have been synthesized successfully for x=6.5 and 7.0. The crystal structure and magnetic properties of the Gd3Co29−xCrx compounds have been investigated by x-ray diffraction analysis and magnetic measurements. It has been found that Gd3(Co,Cr)29 with x=6.5 and 7.0 are of ferrimagnetic compounds with Curie temperature of 412 K for x=6.5 and 359 K for x=7.0, respectively. Temperature dependence of the magnetization shows a compensation point of the magnetization at the certain temperature below the Curie temperature. The intersublattice molecular field coefficient, nRT, was derived to be 3.3 T f.u./μB for Gd3Co22.5Cr6.5 on the basis of the magnetization curve at the compensation temperature. It is noteworthy that the Gd3(Co,Cr)29 compounds exhibit favorable easy-axis anisotropy in the whole temperature range below Curie temperature. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    British journal of dermatology 148 (2003), S. 0 
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Background Pachyonychia congenita (PC) is a group of autosomal dominant ectodermal dysplasias caused by mutations in four differentiation-specific keratin genes. Two major clinical subtypes of PC have been generally recognized. Symmetrically thickened fingernails and toenails are the defining characteristic of PC type 2 (PC-2) with onset at infancy. Pilosebaceous cysts are the best hallmark of PC-2, but they usually occur at puberty. Objectives To report a Chinese pedigree of PC-2 with unusually early onset sebaceous cysts and to explore the genetic mutation and its phenotype. Methods Exon 1 of keratin 17 was amplified by polymerase chain reaction (PCR) from genomic DNA from the three patients in the pedigree, the proband, his half-sister and his younger son, two unaffected members in the pedigree and 50 unrelated and unaffected people. PCR products were directly sequenced to detect the mutation. Results Direct sequencing of the PCR products revealed a heterozygous 275A→G mutation in all three affected members. This mutation predicts the substitution of asparagine by serine in codon 92 (N92S) located in the 1A domain of keratin 17. Conclusions Mutation in the 1A domain of keratin 17 underlies the affected members' phenotype, PC-2 with early onset sebaceous cysts and late-onset thickened fingernails and toenails. The onset of the cysts is very early in some people within this family and the age at onset of thickened fingernails and toenails is variable within the family, implying the existence of modifying factors.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Chromatography B: Biomedical Sciences and Applications 581 (1992), S. 139-142 
    ISSN: 0378-4347
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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