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Anti-U and haemolytic disease of the fetus and newborn (1998)

Smith, G. ; Knott, P. ; Rissik, J. ; [et al.]

Oxford, UK : Blackwell Publishing Ltd

BJOG 105 (1998), S. 0

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ISSN: 1471-0528

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: The red cell alloantibody, anti-U, is uncommon but is a recognised cause of haemolytic disease of the fetus and newborn. We describe six pregnancies complicated by the presence of maternal anti-U, and review nine other well-documented cases. In these 15 cases severe haemolytic disease occurred only with titres of ≥ 1/512, and titres as high as 1/4000 were not necessarily associated with significant haemolysis. We recommend that an anti-U titre of ≥ 1/128 or more at ≥ 17 weeks of gestation is an indication for assessment of haemolysis in the fetus. Amniocentesis is the preferred initial investigation.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1111/j.1471-0528.1998.tb10013.x

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