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  • 1
    Electronic Resource
    Electronic Resource
    Encainide (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Cardiovascular drug reviews 1 (1983), S. 0 
    Details
    ISSN: 1527-3466
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1527-3466.1983.tb00444.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Automatic Implantable Cardioverter Defibrillator: Surgical Approaches for Implantation (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiac surgery 7 (1992), S. 0 
    Details
    ISSN: 1540-8191
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Surgical approaches for implantation of the automatic cardioverter defibrillator are sternotomy, left thoracotomy, subxiphoid, and subcostal. Although any one of these may be combined with insertion of one or more of the electrodes transvenously, surgical entry into the chest is required for every noninvestigational defibrillator implantation operation. The approaches differ in exposure provided for selecting electrode sites and for handling untoward events, in amount and location of tissue that must be divided or dissected, and in average time required. The operation is an electrical one. Its purpose is to obtain reliable rhythm sensing so that defibrillation or cardioversion shocks will occur only when necessary, and to obtain low enough defibrillation thresholds for shocks of 30 joules or less to have a 10-joule defibrillation safety margin. Many of the patients have had previous cardiac operations. They usually have low or very low ejection fractions. lntraoperative electrophysiological testing with often multiple defibrillation episodes is required. The choice of approach varies with the state of the patient, the institutional experience, and the surgeon. This article describes techniques, and the advantages and disadvantages of the four approaches as used by four surgeons in four different institutions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8191.1992.tb00804.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Implantable Cardioverter Defibrillator: (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiovascular electrophysiology 4 (1993), S. 0 
    Details
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Implantable Cardioverter Defibrillator. The Ventritex® Cadence® Model V-100 Tiered Therapy Defibrillator is a third generation antitachyarrhythmia device currently completing clinical trials in the United States. The implantable pulse generator is capable of high energy detibrillation, low energy cardioversion, as well as antitachycardia and bradycardia pacing. In addition, this microprocessor controlled device can deliver monophasic or biphasic defibrillation/cardioversion shocks, is noncommitted to deliver shock therapy after initiating charging for defibrillation or cardioversion therapy, and can store electrograms of spontaneous tachyarrhythmia episodes. These expanded device capabilities should improve therapy efficacy and patient management, and represent a major advance in the treatment of patients with ventricular tachyarrhythmias, (J Cardiovasc Electrophysiol, Vol. 4, pp. 211–223, April 1993)
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8167.1993.tb01225.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Management of Patients with the Automatic Implantable Cardioverter/Defibrillator (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cardiovascular electrophysiology 3 (1985), S. 0 
    Details
    ISSN: 1540-8167
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1540-8167.1985.tb01678.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    CLINICAL EFFICACY OF ANTIARRHYTHMIC DRUGS IN PREVENTION OF SUDDEN CORONARY DEATH (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 382 (1982), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1982.tb55223.x
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Technological Status and Problems of Ambulatory Electrocardiographic Monitoring (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 432 (1984), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1984.tb14513.x
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Role of concentration-dependent plasma protein binding in disopyramide disposition (1979)
    Springer
    Journal of pharmacokinetics and pharmacodynamics 7 (1979), S. 29-46 
    Details
    ISSN: 1573-8744
    Keywords: nonlinear disposition ; plasma protein binding ; disopyramide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Plasma disopyramide concentration-time data and plasma protein binding measurements were obtained in 12 patients requiring disopyramide for suppression of their cardiac arrhythmias. The fraction of disopyramide unbound to plasma proteins varies from approximately 0.19 to 0.46 over the therapeutic range of total plasma concentrations (2–8 mg/liter). Data from single and multiple intravenous doses were analyzed using two models based on the hypothesis either that clearance is independent of the total disopyramide plasma concentration (total clearance model) or that clearance is independent of the concentration of disopyramide unbound to plasma proteins (free clearance model). This analysis indicates that only the free clearance model satisfactorily describes the data as a linear system. Using the free clearance model and data obtained from single doses, multiple intravenous infusions were designed for each patient which would rapidly attain and maintain predetermined plasma disopyramide concentrations. The calculated and observed disopyramide concentrations were in close agreement. In the 12 patients studied, at any given total disopyramide plasma concentration, there was an approximately twofold range in the fraction of disopyramide unbound to plasma proteins. Mean plasma protein binding data are therefore of little value in a given patient for predicting free disopyramide concentrations from measurements of total disopyramide concentration. Difficulties in the clinical management of patients receiving disopyramide, resulting from the nonlinear disposition of the usually measured total disopyramide concentrations, are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01059439
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    Paper (German National Licenses)
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